DNA vaccines : types, advantages, and limitations
DNA vaccines : types, advantages, and limitations [E-Book]
- 1 online resource.
- Immunology and immune system disorders .
- Immunology and immune system disorders. .
Includes bibliographical references and index.
DNA VACCINES: TYPES, ADVANTAGES AND LIMITATIONS ; IMMUNOLOGY AND IMMUNE SYSTEM DISORDERS ; DNA VACCINES: TYPES, ADVANTAGES AND LIMITATIONS ; Contents ; Preface ; Novel Carrier Adjuvant for DNA Vaccination ; Abstract ; 1. Introduction ; 2. Immunology of DNA Vaccines: Mode of Action and Immune Response Induction ; 3. Barriers in DNA Vaccine Delivery and Possible Modes to Overcome these Barriers ; 4. Novel Strategies for DNA Delivery ; 4.1. Lipid Based Carrier Adjuvants for DNA Vaccination ; 4.1.1. Liposomes ; 4.1.2. Virosomes. 4.2. Polymers and Polymeric Carriers Systems 4.2.1. Polyethylenimine ; 4.2.2. Polylysine ; 4.2.3. Chitosan ; 4.2.4. Dendrimers ; 5. Concluding Remark and Future Prospects ; References ; Improving the Immunogenicity of DNA Vaccines: A Nano-Sized Task? ; Abstract ; Introduction ; Improving Immunogenicity of Plasmid DNA Vaccines ; Routes of Delivery of Plasmid DNA Vaccines ; Physical Delivery Systems of Plasmid DNA Vaccines ; Needle-Free Delivery Methods ; Expression Optimization ; Cytokines ; Delivery Vectors for DNA Vaccines ; Bacterial Vectors ; Viral Vectors. DNA and RNA Replicons Nano-Sized Vehicles for Gene Delivery ; Inorganic to Biomaterial -- Past to Future ; Size Determines the Fate of Particles ; Conclusion ; References ; Novel Delivery Strategies for DNA ; Abstract ; I. Introduction ; II. Optimization of Immunogenicity of DNA Vaccines ; 2.1. Choice of Targets and Expression Plasmid for DNA Vaccines ; 2.2. Selection of High Expression Plasmids for DNA Vaccines ; 2.3. Codon Optimization for Higher Gene Expression ; 2.4. Adjuvant Choice for DNA Vaccines ; III. DNA Delivery Strategies ; 3.1. Invasive Delivery. 3.1.1. Needle Injection 3.1.2. In Vivo Electroporation ; 3.1.3. Tattoo Gun Delivery ; 3.2. Non-Invasive Topical Delivery Method ; 3.2.1. Tape Stripping ; 3.2.2. Nanopatch Delivery ; 3.2.3. Nano-Particle Mediated Delivery ; 3.3. Viral-Mediated DNA Delivery Systems ; 3.4. Non-Viral Gene Delivery Systems ; 3.5. Novel Delivery Methods ; 3.5.1. Laser Mediated Delivery ; 3.5.2. Ultrasound Mediated Delivery System ; III. Future Directions ; References ; Recent Advances in DNA Vaccines ; Abstract ; Introduction ; DNA Vaccines X Traditional Vaccine Approaches ; Components of a DNA Vaccine. How DNA Vaccines Work Delivery Methods ; Advantages X Limitations ; Strategies to Enhance Immunogenicity of DNA Vaccines ; Modifications of Plasmid Basic Design ; Delivery Methods ; Target to Dendritic Cells ; Improved Immunization Protocols ; Adjuvants ; Conclusion ; References ; Co-Administration of Gamma Interferon Gene with DNA Vaccine Expressing Duck Hepatitis B Virus (DHBV) Proteins Enhances Therapeutic Efficacy of DNA-Based Immunization in Chronic Virus Carriers ; Abstract ; Introduction ; Materials and Methods ; Animals ; DNA Immunization.
9781620810453 162081045X
2019714320
015875048 Uk
DNA vaccines.
Vaccines, DNA.
QW 805
Includes bibliographical references and index.
DNA VACCINES: TYPES, ADVANTAGES AND LIMITATIONS ; IMMUNOLOGY AND IMMUNE SYSTEM DISORDERS ; DNA VACCINES: TYPES, ADVANTAGES AND LIMITATIONS ; Contents ; Preface ; Novel Carrier Adjuvant for DNA Vaccination ; Abstract ; 1. Introduction ; 2. Immunology of DNA Vaccines: Mode of Action and Immune Response Induction ; 3. Barriers in DNA Vaccine Delivery and Possible Modes to Overcome these Barriers ; 4. Novel Strategies for DNA Delivery ; 4.1. Lipid Based Carrier Adjuvants for DNA Vaccination ; 4.1.1. Liposomes ; 4.1.2. Virosomes. 4.2. Polymers and Polymeric Carriers Systems 4.2.1. Polyethylenimine ; 4.2.2. Polylysine ; 4.2.3. Chitosan ; 4.2.4. Dendrimers ; 5. Concluding Remark and Future Prospects ; References ; Improving the Immunogenicity of DNA Vaccines: A Nano-Sized Task? ; Abstract ; Introduction ; Improving Immunogenicity of Plasmid DNA Vaccines ; Routes of Delivery of Plasmid DNA Vaccines ; Physical Delivery Systems of Plasmid DNA Vaccines ; Needle-Free Delivery Methods ; Expression Optimization ; Cytokines ; Delivery Vectors for DNA Vaccines ; Bacterial Vectors ; Viral Vectors. DNA and RNA Replicons Nano-Sized Vehicles for Gene Delivery ; Inorganic to Biomaterial -- Past to Future ; Size Determines the Fate of Particles ; Conclusion ; References ; Novel Delivery Strategies for DNA ; Abstract ; I. Introduction ; II. Optimization of Immunogenicity of DNA Vaccines ; 2.1. Choice of Targets and Expression Plasmid for DNA Vaccines ; 2.2. Selection of High Expression Plasmids for DNA Vaccines ; 2.3. Codon Optimization for Higher Gene Expression ; 2.4. Adjuvant Choice for DNA Vaccines ; III. DNA Delivery Strategies ; 3.1. Invasive Delivery. 3.1.1. Needle Injection 3.1.2. In Vivo Electroporation ; 3.1.3. Tattoo Gun Delivery ; 3.2. Non-Invasive Topical Delivery Method ; 3.2.1. Tape Stripping ; 3.2.2. Nanopatch Delivery ; 3.2.3. Nano-Particle Mediated Delivery ; 3.3. Viral-Mediated DNA Delivery Systems ; 3.4. Non-Viral Gene Delivery Systems ; 3.5. Novel Delivery Methods ; 3.5.1. Laser Mediated Delivery ; 3.5.2. Ultrasound Mediated Delivery System ; III. Future Directions ; References ; Recent Advances in DNA Vaccines ; Abstract ; Introduction ; DNA Vaccines X Traditional Vaccine Approaches ; Components of a DNA Vaccine. How DNA Vaccines Work Delivery Methods ; Advantages X Limitations ; Strategies to Enhance Immunogenicity of DNA Vaccines ; Modifications of Plasmid Basic Design ; Delivery Methods ; Target to Dendritic Cells ; Improved Immunization Protocols ; Adjuvants ; Conclusion ; References ; Co-Administration of Gamma Interferon Gene with DNA Vaccine Expressing Duck Hepatitis B Virus (DHBV) Proteins Enhances Therapeutic Efficacy of DNA-Based Immunization in Chronic Virus Carriers ; Abstract ; Introduction ; Materials and Methods ; Animals ; DNA Immunization.
9781620810453 162081045X
2019714320
015875048 Uk
DNA vaccines.
Vaccines, DNA.
QW 805