Bladder cancer : risk factors, emerging treatment strategies and challenges

Bladder cancer : risk factors, emerging treatment strategies and challenges [E-Book] - 1 online resource. - Cancer etiology, diagnosis and treatments . - Cancer etiology, diagnosis, and treatments. .

Includes bibliographical references and index.

Cancer stem cell (CSC) in bladder malignancy / The five senses in bladder cancer diagnostics / Bladder cancer in pediatric patients / Multi-tasking chemoinformatic model for the efficient discovery of potent and safer anti-bladder cancer agents / Long non coding mitochondrial RNAs as potential targets for diagnosis and therapy of bladder cancer / Histological variants of urothelial carcinoma / Novel therapeutic modalities in patients with advanced or metastatic urothelial carcinoma / Jianmin Zhang Caterina Gulia Santiago Vallasciani Alejandro Speck-Planche and M. N. D. S. Cordeiro -- Jamie Villegas Hyung Suk Kin and Ja Hyeon Ku -- Kazumasa Matsumoto (and two others) -- (and four others) -- (and four others) -- (and ten others) -- (and four others).

Bladder cancer is the fifth most common form of cancer worldwide and is mainly prevalent in developed countries. It is thought to arise through two distinct pathways: the noninvasive and the invasive. The noninvasive pathway gives rise to a superficial papillary carcinoma that is characterized by activating mutations in oncogenes such as H-ras, FGFR3 and PI3K. This pathway is rarely lethal as superficial papillary carcinomas can be readily removed through transurethral resection. However, 15% of noninvasive urothelial tumors can transform into invasive carcinomas and have high recurrence 80%.--

9781633216709 1633216705

2020676542


Bladder--Cancer.
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