Clinical intensive care medicine
Clinical intensive care medicine [E-Book]
- 1 online resource.
- Introductory series in medicine ; volume 1 .
- Introductory series in medicine ; v. 1. .
Includes bibliographical references and index.
Foreword from the Series Editor; Foreword; Preface; List of Authors; 1 History of Intensive Care; References; 2 Cardiovascular Physiology; 2.1 Introduction; 2.2 The Cardiac Cycle; 2.3 Ventricular Performance and the Determinants of Cardiac Output; 2.3.1 Ventricular preload; 2.3.2 Ventricular afterload; 2.3.3 Venticular contractility and stroke work; 2.3.4 Stroke volume; 2.3.5 Heart rate; 2.3.6 Ventricular interdependence; 2.4 Coronary Blood Flow; 2.5 Peripheral Circulation; 2.6 The Microcirculation; 2.7 Clinical Case; 2.7.1 What is the diagnosis?; 2.7.2 What next? 2.7.3 Lessons to learnReferences; 3 Respiratory Physiology; 3.1 Introduction; 3.2 Regulation of Respiration; 3.3 Mechanics of Ventilation; 3.4 Work of Breathing; 3.5 Ventilation-Perfusion; 3.6 Carbon Dioxide and Interpretation of Expired Alveolar Gas; 3.7 Blood Gases; 3.8 Physiological Effects of Positive-Pressure Ventilation; 3.8.1 Effects on the lungs; 3.8.2 Effects on surfactant; 3.8.3 Effect on the cardiovascular system; 3.8.4 Effect on lymphatics; 3.8.5 Effects on fluid balance; References; 4 Cellular Physiology in Critical Care; 4.1 Oxygen Delivery and Cellular Utilisation. 4.1.1 Mitochondria4.1.1.1 Energy transduction; 4.1.1.2 The mitochondrial respiratory chain; 4.1.2 Control of cellular respiration; 4.1.2.1 Nitric oxide; 4.1.3 Sepsis and mitochondria activity; 4.1.4 Mitochondrial inhibitors; 4.1.4.1 Carbon monoxide; 4.1.4.2 Alcohols; 4.1.4.3 Cyanide; 4.1.4.4 Propofol; 4.1.4.5 Metformin; 4.1.4.6 Statins; 4.1.4.7 Nucleos(t)ide; 4.2 Cell Death in Critical Care; 4.2.1 Apoptosis; 4.2.2 Necrosis; 4.3 Conclusion; 4.4 Clinical Scenario; 4.4.1 History; 4.4.2 Investigations; 4.4.3 Progress; 4.4.4 Further progress; 4.4.5 Answers; References; 5 Cardiovascular Monitoring. 5.1 Purpose of Monitoring5.2 Clinical Examination and Non-Invasive Monitoring; 5.3 Pulse Oximetry; 5.4 Venous Saturations; 5.5 Pulmonary Artery Flotation Catheter; 5.6 Pulse Contour Analysis; 5.7 Oesophageal Doppler; 5.8 Echocardiography; 5.9 Current Approach to Monitoring the Critically Ill Patient; 5.10 Clinical Case; 5.10.1 Comment; References; 6 Vasoactive Agents; 6.1 Definitions; 6.2 The Pressure versus Flow Dilemma; 6.3 Tissue Oxygen Consumption and Supply; 6.3.1 Oxygen supply; 6.3.2 Oxygen consumption; 6.4 Vasodilators: Rationale and Current Treatments; 6.4.1 Nitrates. 6.4.1.1 Glyceryl trinitrate6.4.1.2 Nitroprusside; 6.4.2 Nesiritide; 6.4.3 Nifedipine; 6.4.4 Nicardipine; 6.4.5 Esmolol; 6.4.6 Labetolol; 6.4.7 Hydralazine; 6.4.8 Phentolamine; 6.5 Vasoconstrictors: Rationale and Current Agents; 6.5.1 Noradrenaline; 6.5.2 Dopamine; 6.5.3 Adrenaline; 6.5.4 Vasopressin; 6.5.5 Phenylephrine; 6.5.6 Ephedrine; 6.5.7 Metaraminol; 6.6 Cardiac Output: Advantages and Disadvantages of Pharmacological Augmentation; 6.6.1 Adrenaline; 6.6.2 Dobutamine; 6.6.3 Dopexamine; 6.6.4 Dopamine; 6.6.5 Phosphodiesterase inhibitors; 6.6.6 Levosimendan; 6.6.7 Isoprenaline.
Intensive care patients are the most critically ill in any hospital and they are a patient group that utilises a disproportionate amount of medical resources. Intensive care medicine, around for about 40 years, is a relatively recent but globally expanding specialty due to a growing geriartric population of discerning demand for health system. The older generation of intensivists are approaching retirement. The middle generation is trained in various medical specialties and then subspecialised in intensive care. These doctors now lead the way in clinical practice, research, management and trai.
9781848163898 1848163894
Critical care medicine.
Clinical medicine.
Critical Care
Clinical Medicine
Critical Illness--therapy
WX 218
Includes bibliographical references and index.
Foreword from the Series Editor; Foreword; Preface; List of Authors; 1 History of Intensive Care; References; 2 Cardiovascular Physiology; 2.1 Introduction; 2.2 The Cardiac Cycle; 2.3 Ventricular Performance and the Determinants of Cardiac Output; 2.3.1 Ventricular preload; 2.3.2 Ventricular afterload; 2.3.3 Venticular contractility and stroke work; 2.3.4 Stroke volume; 2.3.5 Heart rate; 2.3.6 Ventricular interdependence; 2.4 Coronary Blood Flow; 2.5 Peripheral Circulation; 2.6 The Microcirculation; 2.7 Clinical Case; 2.7.1 What is the diagnosis?; 2.7.2 What next? 2.7.3 Lessons to learnReferences; 3 Respiratory Physiology; 3.1 Introduction; 3.2 Regulation of Respiration; 3.3 Mechanics of Ventilation; 3.4 Work of Breathing; 3.5 Ventilation-Perfusion; 3.6 Carbon Dioxide and Interpretation of Expired Alveolar Gas; 3.7 Blood Gases; 3.8 Physiological Effects of Positive-Pressure Ventilation; 3.8.1 Effects on the lungs; 3.8.2 Effects on surfactant; 3.8.3 Effect on the cardiovascular system; 3.8.4 Effect on lymphatics; 3.8.5 Effects on fluid balance; References; 4 Cellular Physiology in Critical Care; 4.1 Oxygen Delivery and Cellular Utilisation. 4.1.1 Mitochondria4.1.1.1 Energy transduction; 4.1.1.2 The mitochondrial respiratory chain; 4.1.2 Control of cellular respiration; 4.1.2.1 Nitric oxide; 4.1.3 Sepsis and mitochondria activity; 4.1.4 Mitochondrial inhibitors; 4.1.4.1 Carbon monoxide; 4.1.4.2 Alcohols; 4.1.4.3 Cyanide; 4.1.4.4 Propofol; 4.1.4.5 Metformin; 4.1.4.6 Statins; 4.1.4.7 Nucleos(t)ide; 4.2 Cell Death in Critical Care; 4.2.1 Apoptosis; 4.2.2 Necrosis; 4.3 Conclusion; 4.4 Clinical Scenario; 4.4.1 History; 4.4.2 Investigations; 4.4.3 Progress; 4.4.4 Further progress; 4.4.5 Answers; References; 5 Cardiovascular Monitoring. 5.1 Purpose of Monitoring5.2 Clinical Examination and Non-Invasive Monitoring; 5.3 Pulse Oximetry; 5.4 Venous Saturations; 5.5 Pulmonary Artery Flotation Catheter; 5.6 Pulse Contour Analysis; 5.7 Oesophageal Doppler; 5.8 Echocardiography; 5.9 Current Approach to Monitoring the Critically Ill Patient; 5.10 Clinical Case; 5.10.1 Comment; References; 6 Vasoactive Agents; 6.1 Definitions; 6.2 The Pressure versus Flow Dilemma; 6.3 Tissue Oxygen Consumption and Supply; 6.3.1 Oxygen supply; 6.3.2 Oxygen consumption; 6.4 Vasodilators: Rationale and Current Treatments; 6.4.1 Nitrates. 6.4.1.1 Glyceryl trinitrate6.4.1.2 Nitroprusside; 6.4.2 Nesiritide; 6.4.3 Nifedipine; 6.4.4 Nicardipine; 6.4.5 Esmolol; 6.4.6 Labetolol; 6.4.7 Hydralazine; 6.4.8 Phentolamine; 6.5 Vasoconstrictors: Rationale and Current Agents; 6.5.1 Noradrenaline; 6.5.2 Dopamine; 6.5.3 Adrenaline; 6.5.4 Vasopressin; 6.5.5 Phenylephrine; 6.5.6 Ephedrine; 6.5.7 Metaraminol; 6.6 Cardiac Output: Advantages and Disadvantages of Pharmacological Augmentation; 6.6.1 Adrenaline; 6.6.2 Dobutamine; 6.6.3 Dopexamine; 6.6.4 Dopamine; 6.6.5 Phosphodiesterase inhibitors; 6.6.6 Levosimendan; 6.6.7 Isoprenaline.
Intensive care patients are the most critically ill in any hospital and they are a patient group that utilises a disproportionate amount of medical resources. Intensive care medicine, around for about 40 years, is a relatively recent but globally expanding specialty due to a growing geriartric population of discerning demand for health system. The older generation of intensivists are approaching retirement. The middle generation is trained in various medical specialties and then subspecialised in intensive care. These doctors now lead the way in clinical practice, research, management and trai.
9781848163898 1848163894
Critical care medicine.
Clinical medicine.
Critical Care
Clinical Medicine
Critical Illness--therapy
WX 218