Techniques in epidermal biology : an integrated approach to autoimmune skin disease
Cirillo, Nicola, DDS.
Techniques in epidermal biology : an integrated approach to autoimmune skin disease [E-Book] - 1 online resource (viii 178 pages)
Includes bibliographical references (pages 155-168) and index.
Current knowledge on pemphigus pathophysiology -- Patients, sera, and experimental models -- Optimization of the experimental procedures : semi-quantitative LCIF microscopy, C-HSU buffer, and KAD medium -- Study of anti-desmoglein autoimmunity : pemphigus as a desmoglein-remodeling disease -- Role on non-desmoglein and non-igg in pemphigus -- Downstream signaling involved in acantholysis : I. changes in cell cycle and protein phosphorylation -- Downstream signaling involved in acantholysis : II. secretion of proteinases and the specific proteolysis hypothesis of pemphigus -- Microarray analysis of diseased tissues : cell adhesion is down-regulated on the gene level in pemphigus -- Pharmacological block of acantholysis : towards novel therapies for the treatment of pemphigus.
9781536112856 1536112852
Pemphigus--Pathophysiology.
Epidermolysis bullosa--Pathophysiology.
Pemphigus.
Pemphigus
Acantholysis
WR 200 WR 200 / C578t 2012
Techniques in epidermal biology : an integrated approach to autoimmune skin disease [E-Book] - 1 online resource (viii 178 pages)
Includes bibliographical references (pages 155-168) and index.
Current knowledge on pemphigus pathophysiology -- Patients, sera, and experimental models -- Optimization of the experimental procedures : semi-quantitative LCIF microscopy, C-HSU buffer, and KAD medium -- Study of anti-desmoglein autoimmunity : pemphigus as a desmoglein-remodeling disease -- Role on non-desmoglein and non-igg in pemphigus -- Downstream signaling involved in acantholysis : I. changes in cell cycle and protein phosphorylation -- Downstream signaling involved in acantholysis : II. secretion of proteinases and the specific proteolysis hypothesis of pemphigus -- Microarray analysis of diseased tissues : cell adhesion is down-regulated on the gene level in pemphigus -- Pharmacological block of acantholysis : towards novel therapies for the treatment of pemphigus.
9781536112856 1536112852
Pemphigus--Pathophysiology.
Epidermolysis bullosa--Pathophysiology.
Pemphigus.
Pemphigus
Acantholysis
WR 200 WR 200 / C578t 2012