Therapeutic strategies in cancer biology and pathology /

Sherbet, G. V.

Therapeutic strategies in cancer biology and pathology / Gajanan V. Sherbet. - Amsterdam : Elsevier, ©2013. - (xxii, 288 pages) : illustrations - Elsevier insights .

Includes bibliographical references.

RNA Interference in Genetic Regulation -- EMT Associated Gene Targeting -- Therapeutic Deployment of Metastasis-Associated Gene Function -- Genetic Determinants of Tumour and Metastasis Suppression -- Signalling and Transcription Regulators as Prospective Candidates in Cancer Therapy.

Currently, intensive effort is being directed toward the identification of molecular targets that can provide approaches to the development of novel therapeutic strategies in cancer management. This book focuses on metastasis-associated genes, metastasis promoter and suppressor genes, which relate specifically to behavioral alterations of cancer cells in epithelial mesenchymal transition, cancer stem cell maintenance and propagation, and to the acquisition of invasive and metastasis faculty. The function of these genes has implications for cell cycle regulation and cell proliferation and so constitute an essential element in cancer growth and dissemination.

0124165702 9780124165700

9780124165700


Cancer--Molecular aspects.
Cancer--Genetic aspects.
Cancer--Treatment.
Neoplasms--genetics.
Neoplasms--therapy.
Genetic Therapy--methods.
HEALTH & FITNESS--Diseases--General.
MEDICAL--Clinical Medicine.
MEDICAL--Diseases.
MEDICAL--Evidence-Based Medicine.
MEDICAL--Internal Medicine.
Cancer--Genetic aspects.
Cancer--Molecular aspects.
Cancer--Treatment.

RC268.4

616.99/4

2013 I-568 QZ 266
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