MARC details
| 000 -LEADER |
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| fixed length control field |
03142nam a2200325 i 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
140407s2010 enk fo| 001 0 eng|d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| ISBN |
9780521760584 (hardback) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| ISBN |
9780511778414 (ebook) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| ISBN |
9781139832571 (ebook) |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
UkCbUP |
| 060 ## - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
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| Classification number |
WM 402. |
| 245 00 - TITLE STATEMENT |
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| Title |
Next generation antidepressants : |
| Subtitle |
moving beyond monoamines to discover novel treatment strategies for mood disorders |
| Medium |
[E-book] |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
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| Place of production, publication, distribution, manufacture |
Cambridge : |
| Name of producer, publisher, distributor, manufacturer |
Cambridge University Press, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2010. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Physical description |
1 online resource (xi, 137 pages) |
| 490 1# - SERIES TITLE |
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| Series statement |
Cambridge medicine |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc |
Includes bibliographical references and index. |
| 505 ## - CONTENTS |
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| Contents |
1 Current depression landscape: a state of the field today Laurence Mignon and Stephen M. Stahl<br/>2 Novel therapeutic targets for treating affective disorders Eliyahu Dremencov and Thomas Cremers<br/>3 Developing novel animal models of depression Lotte de Groote and Malgorzata Filip and Andrew C. McCreary<br/>4 Translational research in mood disorders: using imaging technologies in biomarker research Jul Lea Shamy and Adam M. Brickman and Chris D. Griesemer and Anna Parachikova and Mark Day<br/>5 Defining depression endophenotypes Lisa H. Berghorst and Diego A. Pizzagalli<br/>6 Genetic and genomic studies of major depressive disorder Roy H. Perlis<br/>7 Medicinal chemistry challenges in the design of next generation antidepressants David P. Rotella<br/>8 Application of pharmacogenomics and personalized medicine for the care of depression Keh-Ming Lin and Chun-Yu Chen and Yu-Jui Yvonne Wan<br/> |
| 520 8# - ABSTRACT |
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| Abstract |
The World Health Organization defines depression as a primary contributor to the global burden of disease and predicts it will become the second leading cause of death by 2020. The need to develop effective therapies has never been so pressing. Current antidepressant drugs have several limitations. This 2010 book looks at the future of mood-disorder research, covering the identification of new therapeutic targets, establishing new preclinical models, new medicinal chemistry opportunities, and fostering greater understanding of genetic influences. These strategies are likely to help build a better picture of the disease process, and lead to new opportunities for patient stratification and treatment. The ultimate goal for this strand of research is to develop more personalized and effective treatments for this chronic and debilitating condition. This is essential reading for all those involved in psychopharmacologic drug development, and mental health clinicians seeking a preview of discoveries soon to influence their practice. |
| 650 #0 - SUBJECT HEADINGS |
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| Subject term |
Antidepressive agents |
| 9 (RLIN) |
5239 |
| 650 #0 - SUBJECT HEADINGS |
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| Subject term |
Psychopharmacology |
| 650 #0 - SUBJECT HEADINGS |
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| Subject term |
Depression |
| 650 #0 - SUBJECT HEADINGS |
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| Subject term |
Psychotropic drugs |
| 9 (RLIN) |
7615 |
| 650 #0 - SUBJECT HEADINGS |
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| Subject term |
Drug therapy |
| 650 #0 - SUBJECT HEADINGS |
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| Subject term |
Prescription, drug |
| 700 1# - ADDED PERSONAL NAME |
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| Added personal author |
Beyer, Chad E |
| Relator term |
editor |
| 700 1# - ADDED PERSONAL NAME |
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| Added personal author |
Stahl, Stephen M |
| Relator term |
editor |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
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| Uniform title |
Cambridge medicine (Series) |
| 856 40 - ONLINE RESOURCE |
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| Uniform Resource Identifier |
<a href="http://stahlonline.cambridge.org/antidepressants_toc.jsf">http://stahlonline.cambridge.org/antidepressants_toc.jsf</a> |
| Link text |
South London and Maudsley Trust staff and students click here for e-book access (NHS OpenAthens login required) |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Suppress in OPAC |
Do not Suppress in OPAC |