Antiretroviral drug resistance in HIV-1 infected patients with low-level viraemia. (Record no. 75427)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01853cam a2200229 4500 |
| 001 - CONTROL NUMBER | |
| control field | NMDX5953 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 120401t2010 xxu||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mackie, N |
| 240 ## - UNIFORM TITLE | |
| Uniform title | <a href="Journal of Infectious Diseases">Journal of Infectious Diseases</a> |
| 245 ## - TITLE STATEMENT | |
| Title | Antiretroviral drug resistance in HIV-1 infected patients with low-level viraemia. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Date of publication, distribution, etc. | 2010 |
| 500 ## - GENERAL NOTE | |
| General note | NMUH Staff Publications |
| 500 ## - GENERAL NOTE | |
| General note | 201 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | This study characterized the prevalence and patterns of antiretroviral-drug-resistance mutations according to plasma human immunodeficiency virus type 1 (HIV-1) RNA load in a large population of patients with HIV-1 infection who underwent testing for resistance mutations in routine clinical practice. HIV-1 genotypic resistance test results with linked clinical data were obtained from national resistance and clinical databases in the United Kingdom. Among 7861 tests, detection of ⩾1 resistance mutation was most frequent at viral loads of 300–10,000 copies/mL and decreased statistically significantly at viral loads of &gt;10,000 copies/mL. Major resistance mutations were commonly detected in the subset of tests that were performed among patients with viral loads of &lt;1000 copies/mL (1001 [12.7%] of 7861 tests).We conclude that HIV-1 genotypic resistance testing is informative for patients with low viral loads. &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;&nbsp; |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Phillips, A.N. |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kaye, S |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Booth, C. |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Geretti, A.M. |
| 710 ## - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | UK Resistance Database |
| 710 ## - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | UK Collaborative HIV Cohort Study |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://jid.oxfordjournals.org/content/201/9/1303.long">http://jid.oxfordjournals.org/content/201/9/1303.long</a> |
| Withdrawn status | Lost status | Damaged status | Not for loan | Collection code | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Staff publications for NMDX | Ferriman information and Library Service (North Middlesex) | Ferriman information and Library Service (North Middlesex) | Shelves | 07/06/2022 | 07/06/2022 | 07/06/2022 | Book |