Maternal and neonatal outcomes of spontaneously conceived pregnancies in mothers over 45 years: a review of the literature. (Record no. 75821)

MARC details
000 -LEADER
fixed length control field 04695cam a2200253 4500
001 - CONTROL NUMBER
control field NMDX6665
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 120401t2012 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 09320067
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Wong-Taylor, L.A.
240 ## - UNIFORM TITLE
Uniform title <a href="Archives of Gynecology and Obstetrics">Archives of Gynecology and Obstetrics</a>
245 ## - TITLE STATEMENT
Title Maternal and neonatal outcomes of spontaneously conceived pregnancies in mothers over 45 years: a review of the literature.
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Date of publication, distribution, etc. 2012
500 ## - GENERAL NOTE
General note NMUH Staff Publications
500 ## - GENERAL NOTE
General note 285
520 ## - SUMMARY, ETC.
Summary, etc. &lt;div style="line-height: 17.999801635742188px;"&gt;&lt;h4 style="font-size: 1em; font-family: arial, helvetica, clean, sans-serif; margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left;"&gt;PURPOSE:&lt;/h4&gt;&lt;p style="margin: 0px 0px 0.5em;"&gt;&lt;span style="font-size: 8pt;"&gt;There is little published data on&amp;nbsp;&lt;span class="highlight"&gt;pregnancy&lt;/span&gt;&amp;nbsp;&lt;span class="highlight"&gt;outcomes&lt;/span&gt;&amp;nbsp;in women who had&amp;nbsp;&lt;span class="highlight"&gt;conceived&lt;/span&gt;&amp;nbsp;&lt;span class="highlight"&gt;spontaneously&lt;/span&gt;&amp;nbsp;after age&amp;nbsp;&lt;span class="highlight"&gt;45&lt;/span&gt;&amp;nbsp;&lt;span class="highlight"&gt;years&lt;/span&gt;. The aim of this&lt;span class="highlight"&gt;review&lt;/span&gt;&amp;nbsp;is to provide accurate information on the risks and probable&amp;nbsp;&lt;span class="highlight"&gt;outcomes&lt;/span&gt;&amp;nbsp;of&amp;nbsp;&lt;span class="highlight"&gt;spontaneously&lt;/span&gt;&amp;nbsp;&lt;span class="highlight"&gt;conceived&lt;/span&gt;&amp;nbsp;&lt;span class="highlight"&gt;pregnancies&lt;/span&gt;&amp;nbsp;in women&amp;nbsp;&lt;span class="highlight"&gt;over&lt;/span&gt;&amp;nbsp;the age of&amp;nbsp;&lt;span class="highlight"&gt;45&lt;/span&gt;&lt;span class="highlight"&gt;years&lt;/span&gt;, which will enable clinicians to counsel such women appropriately, carry out adequate risk assessment, and ensure better care for&amp;nbsp;&lt;span class="highlight"&gt;pregnancies&lt;/span&gt;in this population.&lt;/span&gt;&lt;/p&gt;&lt;h4 style="margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left;"&gt;&lt;span style="font-size: 8pt;"&gt;DESIGN:&lt;/span&gt;&lt;/h4&gt;&lt;p style="margin: 0px 0px 0.5em;"&gt;&lt;span style="font-size: 8pt;"&gt;A&amp;nbsp;&lt;span class="highlight"&gt;literature&lt;/span&gt;&amp;nbsp;search was performed using EmBase and PubMed for English language articles published between 1970 and 2011, with extractable data on&amp;nbsp;&lt;span class="highlight"&gt;mothers&lt;/span&gt;&amp;nbsp;aged ≥&lt;span class="highlight"&gt;45&lt;/span&gt;&amp;nbsp;at the time of delivery and with ≥95% spontaneous conception in the study population.&lt;/span&gt;&lt;/p&gt;&lt;h4 style="margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left;"&gt;&lt;span style="font-size: 8pt;"&gt;RESULTS:&lt;/span&gt;&lt;/h4&gt;&lt;p style="margin: 0px 0px 0.5em;"&gt;&lt;span style="font-size: 8pt;"&gt;Six such studies with a total pooled number of 505 women were identified. Overall, there is increased&amp;nbsp;&lt;span class="highlight"&gt;maternal&lt;/span&gt;&amp;nbsp;morbidity and rates of caesarean section, as well as higher incidence of premature births and admission to special care baby unit. Contrary to popular belief, career is not always an important factor in delaying childbearing, especially in developing countries. Other factors may include cultural acceptance of large families and lack of contraception, although more research may be carried out in order to explain these hypotheses.&lt;/span&gt;&lt;/p&gt;&lt;h4 style="margin: 0px 0.25em 0px 0px; text-transform: uppercase; float: left;"&gt;&lt;span style="font-size: 8pt;"&gt;CONCLUSION:&lt;/span&gt;&lt;/h4&gt;&lt;p style="margin: 0px 0px 0.5em;"&gt;&lt;span style="font-size: 8pt;"&gt;Pooled retrospective data suggest that women who&amp;nbsp;&lt;span class="highlight"&gt;conceived&lt;/span&gt;&amp;nbsp;&lt;span class="highlight"&gt;spontaneously&lt;/span&gt;&amp;nbsp;after the age of&amp;nbsp;&lt;span class="highlight"&gt;45&lt;/span&gt;&amp;nbsp;&lt;span class="highlight"&gt;years&lt;/span&gt;&amp;nbsp;have increased&amp;nbsp;&lt;span class="highlight"&gt;maternal&lt;/span&gt;morbidity and rates of caesarean section, as well as higher incidence of premature births and admission to special care baby unit.&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Lawrence, A.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Cowen, S.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Jones, H.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Nauta, M.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Ramsay-Marcelle, Z.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Yoong, W.
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://www.ncbi.nlm.nih.gov/pubmed/22262490">https://www.ncbi.nlm.nih.gov/pubmed/22262490</a>
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://ferriman.wufoo.com/forms/journal-article-request/">http://ferriman.wufoo.com/forms/journal-article-request/</a>
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