Gallium labelled-prostate-specific membrane antigen-positron emission tomography/computed tomography (GA-PSMA-PET/CT) vs. choline-PET/CT in malignant prostate cancer: a systematic review (Record no. 76589)
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| fixed length control field | 02564cam a2200193 4500 |
| 001 - CONTROL NUMBER | |
| control field | NMDX7810 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 120401t2017 xxu||||| |||| 00| 0 eng d |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Moghul, M. |
| 240 ## - UNIFORM TITLE | |
| Uniform title | <a href="Journal of Endourology">Journal of Endourology</a> |
| 245 ## - TITLE STATEMENT | |
| Title | Gallium labelled-prostate-specific membrane antigen-positron emission tomography/computed tomography (GA-PSMA-PET/CT) vs. choline-PET/CT in malignant prostate cancer: a systematic review |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Date of publication, distribution, etc. | 2017 |
| 500 ## - GENERAL NOTE | |
| General note | NMUH Staff Publications |
| 500 ## - GENERAL NOTE | |
| General note | EMBASE |
| 500 ## - GENERAL NOTE | |
| General note | 31 |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | <span style="font-size: 10pt;"><span style="color: #4a4a4a; font-family: Lato, &quot;Helvetica Neue&quot;, Helvetica, Arial, sans-serif; text-decoration-color: initial;">Introduction&amp;Objective: Recently the role of Prostate-specific membrane antigen-positron emission tomography/computed tomography (PSMA-PET/CT) has become more prominent in helping to diagnose recurrent prostate cancer and malignant prostate cancer. The role of PSMA as a radiotracer appears to be surpassing that of choline tracers in prominent centres. We have evaluated current data regarding the use of PSMA-PET/CT scans compared to Choline PET/CT scans. Materials and Methods: We performed a review of PubMed/Medline, Clinical trials.gov and the Cochrane Library in March 2017 according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement. Results: 4 studies were included in this review having directly compared 68GA-PSMA-PET/CT and Choline PET/CT scans. Choline tracers used were 11C in one study and 18F in the other studies. Overall 230 men had both 68GA-PSMA PET and choline-PET/CT scans. Overall detection rates for biochemical recurrence were 81.1% for GA-PSMA-PET and 70.3% for choline-PET/CT. This indicates that GA-PSMA PET/CT is significantly better than choline-PET/CT for detecting recurrence of prostate cancer (P &lt; 0.005). 68GA-PSMA-PET/CT also showed higher detection rates at lower PSA values. Lesions missed on PSMAPET/CT but captured by choline-PET/CT were found to be negligible (1-2%). Conclusions: 68GA-PSMA-PET/CT appears to offer better diagnostic capability than choline-PET/CT, as well as similar if not higher sensitivities and specificities, indicating justification for replacing choline as the radiotracer of choice in prostate cancer and guiding further management decisions.</span>&nbsp;[Conference abstract]</span> |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rhudd, A. |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rai, B. |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://www.liebertpub.com/doi/pdf/10.1089/end.2017.29029.abstracts">https://www.liebertpub.com/doi/pdf/10.1089/end.2017.29029.abstracts</a> |
| Withdrawn status | Lost status | Damaged status | Not for loan | Collection code | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Date last seen | Price effective from | Koha item type |
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| Staff publications for NMDX | Ferriman information and Library Service (North Middlesex) | Ferriman information and Library Service (North Middlesex) | Shelves | 07/06/2022 | 07/06/2022 | 07/06/2022 | Book |