Sjogren's syndrome: novel insights in pathogenic, clinical and therapeutic aspects

Introduction : history of Sjögren's syndrome -- Clinical features -- Management of Sjögren's syndrome -- Classification criteria for Sjögren's syndrome -- Imaging procedures useful for the diagnosis of Sjögren's syndrome : abnormalities of the major salivary glands -- Sjögren's syndrome--associated lymphoma -- Spontaneous and inducible animal models of Sjögren's syndrome -- Genetics, genomics, gene expression profiling, and epigenetics in Sjögren's syndrome -- Autoantigens and autoantibodies in the pathogenesis of Sjögren's syndrome -- Sjögren's syndrome and environmental factors -- Histology of Sjögren's syndrome -- Glandular epithelium : innocent bystander or leading actor? -- T cells in the pathogenesis of Sjögren's syndrome : more than just Th1 and Th2 -- B lymphocytes in primary Sjögren's syndrome -- Cytokines, chemokines, and the innate immune system in Sjögren's syndrome -- Autoantibodies and autoantigens in Sjögren's syndrome -- Outcome measures in Sjögren's syndrome and perspectives in clinical trial design -- Novel therapeutic strategies in Sjögren's syndrome : b-cell targeting -- Novel therapeutic strategies in Sjögren's syndrome : t-cell targeting -- New biological avenues for Sjögren's syndrome."