Neuromuscular disorders of infancy, childhood, and adolescence: a clinician's approach

Introduction : historical perspectives -- Genetics of neuromuscular disorders -- Electromyography in pediatrics -- Muscle biopsy for diagnosis of neuromuscular and metabolic diseases -- Nerve biopsy -- Neonatal hypotonia -- Arthrogryposis -- Spinal muscular atrophies -- Juvenile amyotrophic lateral sclerosis -- Infectious or acquired motor neuron diseases -- The stiff-man syndrome in children and adolescents -- Radiculopathies and plexopathies -- Congenital and acquired facial palsies -- Mononeuropathies -- Overview of pediatric peripheral neuropathies -- Congenital and early infantile neuropathies -- Hereditary neuropathies in late childhood and adolescence -- Hereditary sensory and autonomic neuropathies -- Peripheral neuropathy in inherited metabolic disease -- Acute polyneuropathies -- Chronic inflammatory demyelinating polyradiculoneuropathy -- Neuropathies secondary to systemic disorders -- Toxic neuropathies -- Hansen's disease (leprosy) : leprous neuropathy -- Acquired presynaptic neuromuscular junction disorders : infant botulism and Lambert-Eaton myasthenic syndrome -- Congenital myasthenic syndromes -- Juvenile and neonatal myasthenia gravis -- Congenital and other structural myopathies -- Congenital muscular dystrophies -- Dystrophinopathies -- Clinical management of dystrophinopathies : a systematic approach -- Facioscapulohumeral dystrophy -- Distal myopathies -- Limb-girdle muscular dystrophies -- Emery-Dreifuss muscular dystrophy : nuclear envelopathies -- Myopathies of systemic disease -- Myotonic dystrophy -- Muscle channelopathies : myotonias and periodic paralyses -- Glycogen storage diseases of muscle -- Lipid storage myopathies due to fatty acid oxidation defects -- Mitochondrial encephalomyopathies -- Juvenile dermatomyositis and other inflammatory myopathies in children -- Neuromuscular problems of the critically ill neonate and child -- Intensive care management, including cardiorespiratory care -- Malignant hyperthermia : an inherited disorder of muscle calcium metabolism -- Disorders of the ocular motor cranial nerves and extraocular muscles -- Oromotor dysfunction in neuromuscular disorders : evaluation and treatment -- Complex regional pain syndromes i and ii (reflex sympathetic dystrophy, causalgia) -- Friedreich ataxia -- Dominantly inherited spinocerebellar syndromes -- Principles and practice of molecular therapies -- Orthopedic management -- Rehabilitation of the child with a neuromuscular disorder -- Outcome measures in neuromuscular diseases.

Neuromuscular disorders are diagnosed across the lifespan and create many challenges especially with infants, children and adolescents. This new edition of the definitive reference, edited by the established world renowned authorities on the science, diagnosis and treatment of neuromuscular disorders in childhood is a timely and needed resource for all clinicians and researchers studying neuromuscular disorders, especially in childhood. The Second Edition is completely revised to remain current with advances in the field and to insure this remains the standard reference for clinical neurologi.