Physiology of the gastrointestinal tract

Volume 1. Section I: Basic cell physiology, genetics, and growth of the GI tract -- Transcription and epigenetic regulation -- Gastrointestinal hormones -- Growth factors in the intestinal tract -- Hedgehog signaling in gastrointestinal morphogenesis and morphostasis -- The role of hippo signaling in intestinal homeostasis -- Notch pathway regulation of intestinal cell fate -- WNT signaling in the intestine: development, homeostasis, disease -- The cell cycle -- Cell death -- Molecular physiology of gastrointestinal function during development -- Section II: Neurogastroenterology. Development of the enteric nervous system -- Enteric neurogenesis -- The physiology and pathophysiology of interstitial cells of Cajal: pacemaking, innervation, and stretch sensation -- Enteric nervous system structure and neurochemistry related to function and neuropathology -- Enteric nervous system: brain-in-the-gut -- Brain processing of gastrointestinal sensory signaling -- Extrinsic sensory afferent nerves innervating the gastrointestinal tract in health and disease -- Neuroimaging of brain-gut interactions in functional gastrointestinal disorders -- Enteric neural regulation of mucosal secretion -- Neuromuscular function in the biliary tract -- Physiology of gastric motility patterns -- Clinical and translational aspects of normal and abnormal motility in the esophagus, small intestine and colon -- Neurophysiologic mechanisms of human large intestinal motility -- Neuromuscular physiology of the pelvic floor -- Section III: Host environmental interaction. Tight junctions and the intestinal barrier -- Gut barrier: adaptive immunity -- Gut barrier: innate immunity -- Chemosensing in the colon -- Mucosal restitution and repair -- Luminal chemosensing and mucosal defenses in the upper GI tract -- Intestinal tuft cells -- Section IV: Gut microbiome. Gastrointestinal microbial ecology with perspectives on health and disease -- Diet effects on gut microbiome composition, function, and host physiology -- Influence of the gut microbiome on immune development during early life -- Gut microbiome and metabolism -- Microbial physiology of the digestive tract and its role in inflammatory bowel diseases.;Volume 2. Section V: Physiology of secretion. Salivary gland secretion -- The cell biology of gastric acid secretion -- Structure-function relationships in the pancreatic acinar cell -- Regulation of pancreatic secretion -- Bile formation and the enterohepatic circulation -- Mechanisms of hepatocyte organic anion transport -- Mechanisms of hepatocyte detoxification -- Physiology of cholngiocytes -- Section VI: Digestion and absorption. Molecular mechanisms of polarized protein trafficking in epithelial cells -- Sugar absorption -- Protein digestion and absorption -- Enterocyte fatty acid handling proteins and chylomicron formation -- Genetic regulation of intestinal lipid transport and metabolism -- Digestion and intestinal absorption of dietary carotenoids and vitamin A -- The vitamin D system: biological and molecular actions in the intestine and colon -- Bioavailability of vitamin E -- Intestinal absorption of vitamin K: cellular and molecular mechanisms -- Intestinal absorption of water-soluble vitamins: cellular and molecular mechanisms -- Water transport in the gastrointestinal tract -- Na+/H+ exchange in mammalian digestive tract -- Intestinal anion absorption -- Ion channels of the gastrointestinal epithelial cells -- Molecular mechanisms of intestinal transport of calcium, phosphate, and magnesium -- Mechanisms and regulation of intestinal iron transport -- Trace metal absorption and transport -- Section VII: Integrated GI physiology and pathophysiology. The gastrointestinal tract and control of food intake -- Mechanisms of helicobacter pylori-induced gastric inflammation -- Host-pathogen interactions in pathophysiology of diarrheal disorders -- Recruitment of inflammatory and immune cells in the gut -- Mechanisms of gastrointestinal malignancies -- Neuropathophysiology of the irritable bowel syndrome -- Pathophysiology of diarrhea and its clinical implications."