Textbook of pediatric rheumatology

Structure and function -- Genetics and pediatric rheumatic diseases -- Mechanistic investigation of pediatric rheumatic diseases -- Inflammation and its mediators -- Adaptive immunity and autoimmunity -- Understanding clinical investigations -- Clinical outcome measures in pediatric rheumatic diseases -- Pain and its assessment -- Imaging in pediatric rheumatic diseases -- Laboratory investigations -- Principles in the management of patients with rheumatic disease -- Global issues in pediatric rheumatology -- Therapeutics : nonbiologics -- Therapeutics : biologics and small molecules -- Nonmedical therapies in pediatric rheumatic diseases -- Juvenile idiopathic arthritis : classification and basic concepts -- Systemic juvenile idiopathic arthritis -- Polyarticular juvenile idiopathic arthritis -- Oligoarticular juvenile idiopathic arthritis -- Enthesitis-related arthritis -- Psoriatic juvenile idiopathic arthritis -- Uveitis in juvenile idiopathic arthritis -- Systemic lupus erythematosus, mixed connective tissue disease, and undifferentiated connective tissue disease -- Antiphospholipid syndrome -- Neonatal lupus erythematosus -- Juvenile dermatomyositis and other inflammatory muscle diseases -- Juvenile systemic sclerosis -- Localized scleroderma and eosinophilic fasciitis -- Sjögren syndrome and immunoglobulin-G disease -- Raynaud phenomenon and vasomotor syndromes -- Inflammatory central nervous system disorders -- Vasculitis and its classification -- Immune complex small-vessel vasculitis : IGA vasculitis (Henoch-Schönlein) and hypersensitivity vasculitis -- Polyarteritis nodosa -- Kawasaki disease -- Antineutrophil cytoplasmic antibody associated vasculitis -- Takayasu arteritis and other vasculitides -- Behçet disease -- Periodic fever syndromes and other inherited autoinflammatory diseases -- Autoinflammatory bone diseases -- Pediatric sarcoidosis -- Macrophage activation syndrome -- Primary immunodeficiencies and rheumatic diseases -- Infectious arthritis and osteomyelitis -- Lyme disease -- Reactive arthritis -- Skeletal malignancies and related disorders -- The impact of rheumatic diseases and their treatment on bone strength development in childhood -- Skeletal dysplasias -- Noninflammatory musculoskeletal pain -- Musculoskeletal manifestations of inflammatory bowel disease -- Musculoskeletal manifestations of systemic disease -- Pain amplification syndromes -- Primary disorders of connective tissue.

Offering up-to-date, comprehensive coverage of disease progression, diagnosis, management, and prognosis, Textbook of Pediatric Rheumatology is the definitive reference in the field. For physicians caring for children with rheumatic diseases, this revised 8th Edition is an unparalleled resource for the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents. Global leaders in the field provide reliable, evidence-based guidance, highlighted by superb full-color illustrations that facilitate a thorough understanding of the science that underlies rheumatic disease. Offers expanded coverage of autoinflammatory diseases, plus new chapters on Takayasu Arteritis and Other Vasculitides, Mechanistic Investigation of Pediatric Rheumatic Diseases, Genetics and Pediatric Rheumatic Diseases, and Global Issues in Pediatric Rheumatology. Reflects the changes in diagnosis, monitoring, and management that recent advances have made possible. Covers the latest information on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies, helping you choose treatment protocols based on the best scientific evidence available today. Features exhaustive reviews of the complex symptoms, signs, and lab abnormalities that characterize these clinical disorders. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.