Diastology: clinical approach to heart failure with preserved ejection fraction

Molecular, gene, and cellular mechanism -- Pathophysiology of heart failure with a preserved ejection fraction: measurements and mechanisms causing abnormal diastolic function -- Role of the pericardium in diastolic dysfunction -- Left atrial function: basic physiology -- Physical determinants of diastolic flow -- Ventricular-arterial interaction in patients with heart failure and a preserved ejection fraction -- General principles, clinical definition, epidemiology, and pathophysiology -- Invasive hemodynamic assessment in heart failure with preserved ejection fraction -- Two-dimensional and doppler evaluation of left ventricular filling, including pulmonary venous flow velocity -- Evaluation of diastolic function by tissue doppler, strain, and torsion analysis -- Color m-mode doppler -- Assessment of left atrial size and function -- Evaluation of intracardiac filling pressures -- Evaluation of right ventricular diastolic function -- Evaluation of diastolic function by cardiac magnetic resonance imaging -- Evaluation of diastolic function by radionuclide techniques -- Diastolic echocardiographic examination -- Diastology stress test -- ASE/EACVI diastolic guidelines: strength and limitations -- Hypertension and its relation to heart failure with a preserved ejection fraction -- Valve disease -- Stage D heart failure with preserved ejection fraction, heart transplantation, and mechanical circulatory support -- Primary restrictive, infiltrative, and storage cardiomyopathies -- Coronary artery disease -- Hypertrophic cardiomyopathy -- Pericardial diseases: constrictive pericarditis and pericardial effusion -- Diastolic function in children and in children with congenital heart disease -- Diabetes mellitus -- Global and regional systolic function of the left ventricle -- Chronotropic incompetence and pacing in HPEF heart failure with preserved ejection fraction -- Aging and heart failure with preserved ejection fraction -- Perioperative assessment of diastolic function -- Pulmonary hypertension in heart failure with preserved ejection fraction -- General treatment of heart failure with preserved ejection fraction and randomized trials -- Echo-based approach to the management of heart failure with preserved ejection fraction -- Future therapies in HFpEF -- Cases of diastolic heart failure -- Review question answers."