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Inherited haemolytic anaemias.

By: Publication details: 2009Uniform titles:
  • Medicine
Online resources: Summary: Congenital red blood cell disorders, affecting their structure or content, result in the premature destruction of the red cell: haemolysis. This damage may be acute or chronic, intravascular or extravascular, and results in anaemia and hyperbilirubinaemia. Some conditions are associated with significant morbidity and mortality, whereas others cause intermittent symptoms and are associated with a normal life expectancy. A better understanding of the pathophysiology, advances in basic science and molecular techniques, improved management of complications, and drug development has led to decreased morbidity and in the case of haemoglobinopathies, improved survival in the developed world.
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NMUH Staff Publications

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Congenital red blood cell disorders, affecting their structure or content, result in the premature destruction of the red cell: haemolysis. This damage may be acute or chronic, intravascular or extravascular, and results in anaemia and hyperbilirubinaemia. Some conditions are associated with significant morbidity and mortality, whereas others cause intermittent symptoms and are associated with a normal life expectancy. A better understanding of the pathophysiology, advances in basic science and molecular techniques, improved management of complications, and drug development has led to decreased morbidity and in the case of haemoglobinopathies, improved survival in the developed world.

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