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An unusual presentation of GIST

By:

Phillips, BL

Publication details: 2012Uniform titles:

Journal of Gastrointestinal Cancer

Online resources:

Summary: Gastrointestinal stromal tumours (GISTs) are rare and constitute only about 1 % of all gastrointestinal (GI) malignant tumours; nevertheless, they are the most common mesenchymal neoplasm of the GI tract. GISTs are typically characterised by positive immunohistochemical staining with CD117 and CD34. Its association with neurofibromatosis (neurofibromatosis 1 (NF-1)) is an unusual event, but people affected by NF-1 are more likely to develop GIST than the general population. Here, we report an unusual presentation of a case of malignant GIST in a young lady who has a background history of neurofibromatosis.

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Item type	Home library	Collection	Class number	Status	Date due	Barcode
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NMUH Staff Publications

Gastrointestinal stromal tumours (GISTs) are rare and constitute only about 1&nbsp;% of all gastrointestinal (GI) malignant tumours; nevertheless, they are the most common mesenchymal neoplasm of the GI tract. GISTs are typically characterised by positive immunohistochemical staining with CD117 and CD34. Its association with neurofibromatosis (neurofibromatosis 1 (NF-1)) is an unusual event, but people affected by NF-1 are more likely to develop GIST than the general population. Here, we report an unusual presentation of a case of malignant GIST in a young lady who has a background history of neurofibromatosis.

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