Gliomas : symptoms, diagnosis and treatment options [E-Book]

Includes bibliographical references and index.

Description based on print version record.

GLIOMAS: SYMPTOMS, DIAGNOSIS AND TREATMENT OPTIONS; Library of Congress Cataloging-in-Publication Data; CONTENTS; INTRODUCTION; SECTION I. SYMPTOMS AND DIAGNOSIS; Chapter 1: EPIDEMIOLOGY OF GLIOMAS; ABSTRACT; INTRODUCTION; INCIDENCE AND MORTALITY; GENETIC FACTORS; ADULT STATURE AND BODY WEIGHT; HORMONAL AND REPRODUCTIVE FACTORS; ALLERGIES AND OTHER MEDICAL CONDITIONS; SMOKING AND ALCOHOL; N-NITROSO COMPOUNDS AND OTHER DIETARY FACTORS; IONIZING RADIATION; CELL PHONE USE; CONCLUSION; REFERENCES; Chapter 2: PATHOLOGY OF GLIOMAS; ABSTRACT; INTRODUCTION; ASTROCYTIC TUMORS; OLIGODENDROGLIAL TUMORS.

CONCLUSIONREFERENCES; Chapter 3: MOLECULAR GENETICS OF BRAIN TUMORS; ABSTRACT; INTRODUCTION; TUMOR SUPPRESSORS, ONCOGENES AND MUTATOR GENES; MUTATIONS THAT UNDERLIE BRAIN TUMORS; GLIOBLASTOMAS; LOW-GRADE ASTROCYTOMAS AND OLIGODENDROGLIOMAS; MEDULLOBLASTOMAS; SUMMARY: PERSPECTIVES IN BRAIN TUMORS GENOMICS; REFERENCES; Chapter 4: CLINICAL FEATURES OF CENTRAL NERVOUS SYSTEM TUMORS; ABSTRACT; INTRODUCTION; CLINICAL PRESENTATION; CONCLUSION; REFERENCES; Chapter 5: NEURO IMAGING OF MALIGNANT GLIOMAS; ABSTRACT; INTRODUCTION; PERFUSION IMAGING; SPECTROSCOPY; DIFFUSION WEIGHTED IMAGING.

BRAIN MAPPING WITH FUNCTIONAL MRI (FMRI)CONCLUSION; REFERENCES; Chapter 6: INTRA-OPERATIVE BRAIN MAPPING IN GLIOMA SURGERY; ABSTRACT; INTRODUCTION; LOCALIZATION OF HUMAN CORTICAL AND SUBCORTICAL FUNCTION; TUMOR AND FUNCTION LOCALIZATION; PREOPERATIVE CONSIDERATIONS; INTRAOPERATIVE MAPPING TECHNIQUES; CONCLUSIONS; REFERENCES; Chapter 7: PREOPERATIVE BRAIN MAPPING IN GLIOMA SURGERY; ABSTRACT; INTRODUCTION; METHODS OF BRAIN MAPPING: ADVANCES AND LIMITATIONS; CONCLUSION; REFERENCES; SECTION II. CURRENT TREATMENT OPTIONS; Chapter 8: NEUROLOGICAL COMPLICATIONS OF GLIOMAS; ABSTRACT; I. INTRODUCTION.

CONCLUSIONREFERENCES; Chapter 9: RADIATION THERAPY IN THE MANAGEMENT OF GLIOMA; ABSTRACT; I. INTRODUCTION; II. RADIOTHERAPY FOR HIGH GRADE GLIOMAS; III. RADIOTHERAPY FOR LOW GRADE GLIOMAS; IV. ADVERSE EFFECTS OF RADIATION THERAPY; V. ADDITIONAL TOPICS; CONCLUSION; REFERENCES; Chapter 10: DOSE RATE MODULATION FOR THE SAFE DELIVERY OF RETREATMENT IRRADIATION IN RECURRENT GLIOMA PATIENTS; ABSTRACT; 1. INTRODUCTION; 2. THE BILOGICAL BASIS FOR DOSE RATE MODULATION; 3. TECHNIQUES FOR THE CLINICAL APPLICATION OF REDUCED -- DOSE-RATE EXTERNAL BEAM RADIOTHERAPY.

4. CLINICAL EXPERENCE FOR DOSE RATE MODULATION AS RECURENT GLIOMA THERAPYCONCLUSION; REFERENCES; Chapter 11: TARGETED THERAPIES FOR MALIGNANT GLIOMAS; ABSTRACT; INTRODUCTION; CHEMOTHERAPY; ALKYLATING AGENTS; MOLECULAR TARGETED THERAPIES; ANTIANGIOGENIC THERAPIES; OTHER MOLECULAR TARGETED THERAPIES; EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) INHIBITORS; PLATELET DERIVED GROWTH FACTOR RECEPTOR (PDGFR)INHIBITORS; INTRACELLULAR SIGNALING PATHWAY INHIBITORS; HISTONE DEACETYLASE (HDAC) INHIBITORS; RESISTANCE TO TARGETED THERAPY AND THE ROLE OF STEM CELLS; TARGETING GLIOMA STEM CELLS; CONCLUSION.

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