TY  - BOOK
AU  - Eisenhauer, Elizabeth A
AU  - Twelves, Chris
AU  - Buyse, Marc
TI  - Phase I cancer clinical trials : a practical guide
SN  - 0198567197
PY  - 2006///
CY  - Oxford
PB  - Oxford University Press
N1  - Introduction; Preclinical data and requirements; Basics of phase I design: first-in-man studies; Ethical issues in phase I cancer trials; Special populations and interaction studies; Statistical designs for first-in-man phase I cancer trials; Writing the protocol; Before you begin; Practical aspects of pharmacokinetics and pharmacodynamics; Running the study; Reporting and interpreting results
ER  -