TY - BOOK AU - Kumar, K. AU - Gill, A. AU - Shafei, R. AU - Wright, J.L. TI - A curious case of cholestasis: oral terbinafine associated with cholestatic jaundice and subsequent erythema nodosum PY - 2014/// N1 - NMUH Staff Publications N2 - <span style="font-size: 10pt;">Terbinafine is a commonly prescribed antifungal agent used in the treatment of trichophytic onychomycosis and chronic cutaneous mycosis that are resistant to other treatments. This case report highlights a rarely documented but important adverse hepatic reaction that was caused by the use of oral terbinafine. A woman in her thirties presented with a 3-week history of jaundice, malaise, itching, nausea, decreased appetite, weight loss, dark orange urine and intermittent non-radiating epigastric pain. She had recently finished a 3-week course of oral terbinafine for a fungal nail infection. Liver biopsy findings were consistent with chronic active hepatitis secondary to a drug reaction. A few days after initial presentation, the patient developed erythema nodosum. Delayed development of erythema nodosum secondary to terbinafine could not be excluded.</span> UR - https://www.ncbi.nlm.nih.gov/pubmed/25480138 UR - http://casereports.bmj.com/content/2014/bcr-2014-205331.long ER -