TY - BOOK AU - Haggerty,Samantha ED - Nova Biomedical (Publishing company) TI - Bladder cancer: risk factors, emerging treatment strategies and challenges T2 - Cancer etiology, diagnosis and treatments SN - 9781633216709 PY - 2014///] CY - New York PB - Nova Biomedical/Nova Science Publishers, Inc. KW - Bladder KW - Cancer N1 - Includes bibliographical references and index; Cancer stem cell (CSC) in bladder malignancy; Jianmin Zhang; (and two others) --; The five senses in bladder cancer diagnostics; Caterina Gulia; (and four others) --; Bladder cancer in pediatric patients; Santiago Vallasciani; (and four others) --; Multi-tasking chemoinformatic model for the efficient discovery of potent and safer anti-bladder cancer agents; Alejandro Speck-Planche and M. N. D. S. Cordeiro --; Long non coding mitochondrial RNAs as potential targets for diagnosis and therapy of bladder cancer; Jamie Villegas; (and ten others) --; Histological variants of urothelial carcinoma; Hyung Suk Kin and Ja Hyeon Ku --; Novel therapeutic modalities in patients with advanced or metastatic urothelial carcinoma; Kazumasa Matsumoto; (and four others) N2 - Bladder cancer is the fifth most common form of cancer worldwide and is mainly prevalent in developed countries. It is thought to arise through two distinct pathways: the noninvasive and the invasive. The noninvasive pathway gives rise to a superficial papillary carcinoma that is characterized by activating mutations in oncogenes such as H-ras, FGFR3 and PI3K. This pathway is rarely lethal as superficial papillary carcinomas can be readily removed through transurethral resection. However, 15% of noninvasive urothelial tumors can transform into invasive carcinomas and have high recurrence 80%.-- UR - https://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=833073 ER -