TY - BOOK AU - Rajagopal,Senthilkumar AU - Murugan,Sengottuvelan TI - Hepatotoxicity: symptoms, management and health implications T2 - Hepatology research and clinical developments SN - 9781634826952 PY - 2015///] CY - New York PB - Nova Biomedical KW - Hepatotoxicology KW - Liver KW - Diseases KW - Diagnosis N1 - Includes bibliographical references and index; Chapter 1: Alcoholic Hepatotoxicity: Symptoms and Managements; Abstract; 1. Introduction; 1.1. Liver; 1.1.1. Regulatory Functions of Liver; 1.2. Liver Toxicity; 1.2.1. Drug Induced Hepatotoxicity; 1.2.2. Marker Enzymes for Hepatotoxicity; 1.3. Alcohol; 1.3.1. Alcohol Metabolism in Liver; 1.3.2. Oxidative Metabolism of Ethanol; 1.3.3. Non-Oxidative Metabolism of Ethanol1.4. Impact of Alcohol on Mitochondrial Functions; 1.5. Alcohol Effects on Erythrocyte; 1.6. Alcohol Effects on Stomach; 1.7. Alcohol Effects on Nervous System; 1.8. Alcohol Effects on the Liver; 2. Symptoms; 2.1. Signs and Symptoms of Alcohol Abuse; 2.2. Signs and Symptoms of Alcoholism; 3. Alcohol Management; 3.1. Initial Care Management; 3.2. Management for Alcohol Abuse; 3.3. Variable Treatments for Alcohol Abuse; 3.4. Herbal Treatments; Conclusion; References; Chapter 2: Potential Role of Polyphenols on Liver Health and Diseases; Abstract; IntroductionProperties, Use, and Classification of Phenolic; Compounds; Classification, Structures, and Sources of Flavonoids; Flavonols; Flavones; Flavan-3-ols; Flavanones and Chalcones; Anthocyanidins/Anthocyanins; Isoflavones; Classification, Structures, and Sources of Non-Flavonoids; Phenolic acids and its derivatives; Hydroxycinnamates; Aglycone forms; Stilbenes; Potential Role of Polyphenols in the Management, Prevention, and Treatment of Liver Diseases; Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH); Alcoholic-related liver diseases; Liver cancer; 1.1.4. Drug Induced Liver Injury1.1.4.1. Rifampicin, Isoniazid (INH) Induced Hepatotoxicity; 1.1.4.2. Non Steroidal Anti-Inflammatory Drugs Induced Hepatotoxicity; 1.1.4.3. Anti HIV Drug Induced Hepatotoxicity; 1.1.4.4. Anti-Hyperlipidemic Drugs Induced Hepatotoxicity; 1.1.4.5. Alpha 1 -- Antitrypsin Deficiency; 1.1.4.6. Aflatoxins; 1.3. Alcohol Induced Liver Injury; 1.4. Nonalcoholic Fatty Liver Damage (NAFLD); 1.4.1. Non-Alcoholic Steatohepatitis; 1.5. Schistosomal Infection Induced Liver Damage; 2. Hepatoprotective Agents; 2.1. Marine Environment; 2.1.1. Marine Algae N2 - Over the past few years, epidemiological studies have revealed that there is an increase of life threatening liver diseases worldwide. It becomes increasingly clear that developments in this field are moving so rapidly toward the creation of new drugs against these maladies. Numerous research articles and books have been published on various aspects of toxicities, symptoms, managements and health implications of the liver. Consequently, a catalogue of collective information of toxicities, various features of natural products, and remedies for the prevention of toxicities is needed. This book de UR - https://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=1023399 ER -