TY - BOOK AU - Cirillo,Nicola TI - Techniques in epidermal biology: an integrated approach to autoimmune skin disease SN - 9781536112856 PY - 2012/// CY - Hauppauge, N.Y. PB - Nova Science Publishers KW - Pemphigus KW - Pathophysiology KW - Epidermolysis bullosa KW - Acantholysis N1 - Includes bibliographical references (pages 155-168) and index; Current knowledge on pemphigus pathophysiology -- Patients, sera, and experimental models -- Optimization of the experimental procedures : semi-quantitative LCIF microscopy, C-HSU buffer, and KAD medium -- Study of anti-desmoglein autoimmunity : pemphigus as a desmoglein-remodeling disease -- Role on non-desmoglein and non-igg in pemphigus -- Downstream signaling involved in acantholysis : I. changes in cell cycle and protein phosphorylation -- Downstream signaling involved in acantholysis : II. secretion of proteinases and the specific proteolysis hypothesis of pemphigus -- Microarray analysis of diseased tissues : cell adhesion is down-regulated on the gene level in pemphigus -- Pharmacological block of acantholysis : towards novel therapies for the treatment of pemphigus UR - https://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=1512140 ER -