TY  - BOOK
AU  - Sherbet,G.V.
TI  - Therapeutic strategies in cancer biology and pathology
T2  - Elsevier insights
SN  - 0124165702
AV  - RC268.4 
U1  - 616.99/4 23
PY  - 2013///
CY  - Amsterdam
PB  - Elsevier
KW  - Cancer
KW  - Molecular aspects
KW  - Genetic aspects
KW  - Treatment
KW  - Neoplasms
KW  - genetics
KW  - therapy
KW  - Genetic Therapy
KW  - methods
KW  - HEALTH & FITNESS
KW  - Diseases
KW  - General
KW  - bisacsh
KW  - MEDICAL
KW  - Clinical Medicine
KW  - Evidence-Based Medicine
KW  - Internal Medicine
KW  - fast
N1  - Includes bibliographical references; RNA Interference in Genetic Regulation -- EMT Associated Gene Targeting -- Therapeutic Deployment of Metastasis-Associated Gene Function -- Genetic Determinants of Tumour and Metastasis Suppression -- Signalling and Transcription Regulators as Prospective Candidates in Cancer Therapy
N2  - Currently, intensive effort is being directed toward the identification of molecular targets that can provide approaches to the development of novel therapeutic strategies in cancer management. This book focuses on metastasis-associated genes, metastasis promoter and suppressor genes, which relate specifically to behavioral alterations of cancer cells in epithelial mesenchymal transition, cancer stem cell maintenance and propagation, and to the acquisition of invasive and metastasis faculty. The function of these genes has implications for cell cycle regulation and cell proliferation and so constitute an essential element in cancer growth and dissemination
ER  -