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Thrombotic thrombocytopenic purpura / [e-book]

By:

Scully, Marie A [author.]

Contributor(s):

Cataland, Spero R [author.]

Series: Fast factsPublisher: Abingdon, Oxford : Karger, 2020Description: 1 online resource (60 pages) : illustrations (colour)ISBN:

9781912776801 (PDF ebook) :

Subject(s):

NLM classification:

WG 540

Online resources:

Eligible NHS OpenAthens account holders click here for access

Summary: Thrombotic thrombocytopenic purpura (TTP) is a rare disorder of the blood coagulation system. In most cases, a lack of the ADAMTS13 enzyme leads to an accumulation of ultra-large von Willebrand factor molecules in the plasma which, in turn, initiate the formation of microscopic thromboses in small blood vessels. TTP is a medical emergency. Timely diagnosis and urgent and effective management are vital - mortality in those untreated is in the region of 90%. The understanding of TTP pathogenesis has increased markedly in recent decades. It is now known that TTP is acquired (immunemediated) or congenital, and that the most common type - the acquired form - predominantly affects women in their 40s. It is also clear that the prompt delivery of plasma exchange saves lives.

Holdings
Item type	Home library	URL	Status
Electronic book	BEH-MHT Library Service Online	Link to resource	Available
Electronic book	CEME Library (NELFT) Online	Link to resource	Available
Electronic book	Croydon Health Services Library Online	Link to resource	Available
Electronic book	David Adams Library (Royal Marsden) Online	Link to resource	Available
Electronic book	Ferriman information and Library Service (North Middlesex) Online	Link to resource	Available
Electronic book	Hirson Library (St Helier) Online	Link to resource	Available
Electronic book	Lewisham and Greenwich NHS Trust Library Online	Link to resource	Available
Electronic book	Newcomb Library at Homerton Healthcare Online	Link to resource	Available
Electronic book	Newham Library (Barts Health) Online	Link to resource	Available
Electronic book	Oxleas NHS Foundation Trust Knowledge Services Online	Link to resource	Available
Electronic book	PRUH Education Centre Library Online	Link to resource	Available
Electronic book	Queen's Hospital Jackie Blanks Library Online	Link to resource	Available
Electronic book	Royal London Library (Barts Health) Online	Link to resource	Available
Electronic book	Sally Howell Library (Epsom) Online	Link to resource	Available
Electronic book	South London and Maudsley Trust Library Online	Link to resource	Available
Electronic book	St Bartholomew's Library (Barts Health) Online	Link to resource	Available
Electronic book	Stenhouse Library Online	Link to resource	Available
Electronic book	Thorpe Coombe Library Online	Link to resource	Available
Electronic book	Whipps Cross Library (Barts Health) Online	Link to resource	Available
Electronic book	Whittington Health Library Online	Link to resource	Available

Also issued in print: 2020.

Includes bibliographical references and index.

Thrombotic thrombocytopenic purpura (TTP) is a rare disorder of the blood coagulation system. In most cases, a lack of the ADAMTS13 enzyme leads to an accumulation of ultra-large von Willebrand factor molecules in the plasma which, in turn, initiate the formation of microscopic thromboses in small blood vessels. TTP is a medical emergency. Timely diagnosis and urgent and effective management are vital - mortality in those untreated is in the region of 90%. The understanding of TTP pathogenesis has increased markedly in recent decades. It is now known that TTP is acquired (immunemediated) or congenital, and that the most common type - the acquired form - predominantly affects women in their 40s. It is also clear that the prompt delivery of plasma exchange saves lives.

Specialized.

Description based on online resource; title from PDF title page (viewed on January 18, 2023).

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