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Sickle cell disease : genetics, management and prognosis [E-Book]

Contributor(s): Series: Recent advances in hematology research seriesPublisher: New York : Nova Biomedical, [2015]Description: 1 online resourceContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9781634828642
  • 163482864X
Subject(s): NLM classification:
  • WH 170
Online resources:
Contents:
SICKLE CELL DISEASE:GENETICS, MANAGEMENTAND PROGNOSIS; SICKLE CELL DISEASE:GENETICS, MANAGEMENTAND PROGNOSIS; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter I:Sickle Cell Disease-Geneticsand Sleep; Abstract; Introduction; Polysomnographic Results; Conclusion; References; Chapter II:Calcium Handling in Red BloodCells of Sickle CellDisease Patients; Abstract; 1. Calcium in RBC and MalariaInfection Success; 2. Hemoglobinopathies and RBCMembrane Properties; 3. Ca2+ in RBCs of SCD Patients; 4. Downstream Targets ofIntracellular Ca2+
5. Ca2+ Influx Pathways As Targetsfor TherapyReferences; Chapter III:Antisickling and RadicalScavenging Activities ofAnthocyanin Extracts from theLeaves of Gardenia TernifoliaSubsp. Jovis-Tonantis (Welw.)Verdc. (Rubiaceae); Abstract; Introduction; Materials and Methods; Results and Discussion; Conclusion; Acknowledgments; References; Chapter IV:Bioactivity of Medicinal PlantsTraditionally Used for theManagement of Sickle CellDisease in Democratic Republicof the Congo: State of the Artand Future Directions; Abstract; Sickle Cell Disease:Pathophysiology and Treatment.
Great Apes Plant Foods As Sources ofNew Antisickling Secondary Metabolites:A Validated HypothesisAntisickling Bioassays: State of the Art; Results of Our Research Program; Conclusion and Future Directions; Acknowledgments; References; Chapter V:Pain, Sexual Activity and PartnerSupport in Jamaicans with SickleCell Disease; Abstract; Background; Overview of Psychosocial Impact onSickle Cell Project; Results and Discussion; Recommendations; Conclusion; References; Blank Page; Index.
Summary: Sickle cell disease (SCD) is a genetic disorder caused by an abnormality of hemoglobin. The disease is characterized by a chronic hemolytic anemia. The search for affordable and accessible medicines mainly from plants and having various modes of actions for managing SCD is a priority in Africa where the disease is endemic. The first chapter in this book reviews children with Sickle Cell Disease (SCD). The authors also present their research that shows that clinically, children with SCD behave differently regarding their genetics. The second chapter gives an overview of the current progress in.
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Includes bibliographical references and index.

Description based on print version record; title from PDF title page, viewed (06/26/2020).

SICKLE CELL DISEASE:GENETICS, MANAGEMENTAND PROGNOSIS; SICKLE CELL DISEASE:GENETICS, MANAGEMENTAND PROGNOSIS; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Chapter I:Sickle Cell Disease-Geneticsand Sleep; Abstract; Introduction; Polysomnographic Results; Conclusion; References; Chapter II:Calcium Handling in Red BloodCells of Sickle CellDisease Patients; Abstract; 1. Calcium in RBC and MalariaInfection Success; 2. Hemoglobinopathies and RBCMembrane Properties; 3. Ca2+ in RBCs of SCD Patients; 4. Downstream Targets ofIntracellular Ca2+

5. Ca2+ Influx Pathways As Targetsfor TherapyReferences; Chapter III:Antisickling and RadicalScavenging Activities ofAnthocyanin Extracts from theLeaves of Gardenia TernifoliaSubsp. Jovis-Tonantis (Welw.)Verdc. (Rubiaceae); Abstract; Introduction; Materials and Methods; Results and Discussion; Conclusion; Acknowledgments; References; Chapter IV:Bioactivity of Medicinal PlantsTraditionally Used for theManagement of Sickle CellDisease in Democratic Republicof the Congo: State of the Artand Future Directions; Abstract; Sickle Cell Disease:Pathophysiology and Treatment.

Great Apes Plant Foods As Sources ofNew Antisickling Secondary Metabolites:A Validated HypothesisAntisickling Bioassays: State of the Art; Results of Our Research Program; Conclusion and Future Directions; Acknowledgments; References; Chapter V:Pain, Sexual Activity and PartnerSupport in Jamaicans with SickleCell Disease; Abstract; Background; Overview of Psychosocial Impact onSickle Cell Project; Results and Discussion; Recommendations; Conclusion; References; Blank Page; Index.

Sickle cell disease (SCD) is a genetic disorder caused by an abnormality of hemoglobin. The disease is characterized by a chronic hemolytic anemia. The search for affordable and accessible medicines mainly from plants and having various modes of actions for managing SCD is a priority in Africa where the disease is endemic. The first chapter in this book reviews children with Sickle Cell Disease (SCD). The authors also present their research that shows that clinically, children with SCD behave differently regarding their genetics. The second chapter gives an overview of the current progress in.

Master record variable field(s) change: 072 - OCLC control number change

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