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Hepatotoxicity : symptoms, management and health implications [E-Book]

Contributor(s): Series: Hepatology research and clinical developments seriesPublisher: New York : Nova Biomedical, [2015]Description: 1 online resourceContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9781634826952
  • 1634826957
Subject(s): Online resources:
Contents:
Chapter 1: Alcoholic Hepatotoxicity: Symptoms and Managements; Abstract; 1. Introduction; 1.1. Liver; 1.1.1. Regulatory Functions of Liver; 1.2. Liver Toxicity; 1.2.1. Drug Induced Hepatotoxicity; 1.2.2. Marker Enzymes for Hepatotoxicity; 1.3. Alcohol; 1.3.1. Alcohol Metabolism in Liver; 1.3.2. Oxidative Metabolism of Ethanol
1.3.3. Non-Oxidative Metabolism of Ethanol1.4. Impact of Alcohol on Mitochondrial Functions; 1.5. Alcohol Effects on Erythrocyte; 1.6. Alcohol Effects on Stomach; 1.7. Alcohol Effects on Nervous System; 1.8. Alcohol Effects on the Liver; 2. Symptoms; 2.1. Signs and Symptoms of Alcohol Abuse; 2.2. Signs and Symptoms of Alcoholism; 3. Alcohol Management; 3.1. Initial Care Management; 3.2. Management for Alcohol Abuse; 3.3. Variable Treatments for Alcohol Abuse; 3.4. Herbal Treatments; Conclusion; References; Chapter 2: Potential Role of Polyphenols on Liver Health and Diseases; Abstract
IntroductionProperties, Use, and Classification of Phenolic; Compounds; Classification, Structures, and Sources of Flavonoids; Flavonols; Flavones; Flavan-3-ols; Flavanones and Chalcones; Anthocyanidins/Anthocyanins; Isoflavones; Classification, Structures, and Sources of Non-Flavonoids; Phenolic acids and its derivatives; Hydroxycinnamates; Aglycone forms; Stilbenes; Potential Role of Polyphenols in the Management, Prevention, and Treatment of Liver Diseases; Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH); Alcoholic-related liver diseases; Liver cancer
1.1.4. Drug Induced Liver Injury1.1.4.1. Rifampicin, Isoniazid (INH) Induced Hepatotoxicity; 1.1.4.2. Non Steroidal Anti-Inflammatory Drugs Induced Hepatotoxicity; 1.1.4.3. Anti HIV Drug Induced Hepatotoxicity; 1.1.4.4. Anti-Hyperlipidemic Drugs Induced Hepatotoxicity; 1.1.4.5. Alpha 1 -- Antitrypsin Deficiency; 1.1.4.6. Aflatoxins; 1.3. Alcohol Induced Liver Injury; 1.4. Nonalcoholic Fatty Liver Damage (NAFLD); 1.4.1. Non-Alcoholic Steatohepatitis; 1.5. Schistosomal Infection Induced Liver Damage; 2. Hepatoprotective Agents; 2.1. Marine Environment; 2.1.1. Marine Algae
Summary: Over the past few years, epidemiological studies have revealed that there is an increase of life threatening liver diseases worldwide. It becomes increasingly clear that developments in this field are moving so rapidly toward the creation of new drugs against these maladies. Numerous research articles and books have been published on various aspects of toxicities, symptoms, managements and health implications of the liver. Consequently, a catalogue of collective information of toxicities, various features of natural products, and remedies for the prevention of toxicities is needed. This book de.
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Includes bibliographical references and index.

Description based on print version record.

Chapter 1: Alcoholic Hepatotoxicity: Symptoms and Managements; Abstract; 1. Introduction; 1.1. Liver; 1.1.1. Regulatory Functions of Liver; 1.2. Liver Toxicity; 1.2.1. Drug Induced Hepatotoxicity; 1.2.2. Marker Enzymes for Hepatotoxicity; 1.3. Alcohol; 1.3.1. Alcohol Metabolism in Liver; 1.3.2. Oxidative Metabolism of Ethanol

1.3.3. Non-Oxidative Metabolism of Ethanol1.4. Impact of Alcohol on Mitochondrial Functions; 1.5. Alcohol Effects on Erythrocyte; 1.6. Alcohol Effects on Stomach; 1.7. Alcohol Effects on Nervous System; 1.8. Alcohol Effects on the Liver; 2. Symptoms; 2.1. Signs and Symptoms of Alcohol Abuse; 2.2. Signs and Symptoms of Alcoholism; 3. Alcohol Management; 3.1. Initial Care Management; 3.2. Management for Alcohol Abuse; 3.3. Variable Treatments for Alcohol Abuse; 3.4. Herbal Treatments; Conclusion; References; Chapter 2: Potential Role of Polyphenols on Liver Health and Diseases; Abstract

IntroductionProperties, Use, and Classification of Phenolic; Compounds; Classification, Structures, and Sources of Flavonoids; Flavonols; Flavones; Flavan-3-ols; Flavanones and Chalcones; Anthocyanidins/Anthocyanins; Isoflavones; Classification, Structures, and Sources of Non-Flavonoids; Phenolic acids and its derivatives; Hydroxycinnamates; Aglycone forms; Stilbenes; Potential Role of Polyphenols in the Management, Prevention, and Treatment of Liver Diseases; Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH); Alcoholic-related liver diseases; Liver cancer

1.1.4. Drug Induced Liver Injury1.1.4.1. Rifampicin, Isoniazid (INH) Induced Hepatotoxicity; 1.1.4.2. Non Steroidal Anti-Inflammatory Drugs Induced Hepatotoxicity; 1.1.4.3. Anti HIV Drug Induced Hepatotoxicity; 1.1.4.4. Anti-Hyperlipidemic Drugs Induced Hepatotoxicity; 1.1.4.5. Alpha 1 -- Antitrypsin Deficiency; 1.1.4.6. Aflatoxins; 1.3. Alcohol Induced Liver Injury; 1.4. Nonalcoholic Fatty Liver Damage (NAFLD); 1.4.1. Non-Alcoholic Steatohepatitis; 1.5. Schistosomal Infection Induced Liver Damage; 2. Hepatoprotective Agents; 2.1. Marine Environment; 2.1.1. Marine Algae

Over the past few years, epidemiological studies have revealed that there is an increase of life threatening liver diseases worldwide. It becomes increasingly clear that developments in this field are moving so rapidly toward the creation of new drugs against these maladies. Numerous research articles and books have been published on various aspects of toxicities, symptoms, managements and health implications of the liver. Consequently, a catalogue of collective information of toxicities, various features of natural products, and remedies for the prevention of toxicities is needed. This book de.

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