Immunology

Introduction to the immune system -- Cells, tissues and organs of the immune system -- Mechanisms of innate immunity -- Complement -- Mononuclear phagocytes in immune defence -- T-cell receptors and major histocompatibility complex molecules -- Antigen presentation -- Cell-mediated cytotoxicity -- B-cell development and the antibody response -- Antibodies -- Immunological tolerance -- Regulation of the immune response -- Immune responses in tissues -- Immunity to viruses -- Immunity to bacteria and fungi -- Immunity to protozoa and worms -- Vaccination -- Primary immunodeficiencies -- Aids, secondary immunodeficiency and immunosuppression -- Autoimmunity and autoimmune disease -- Transplantation and rejection -- Immunity to cancers -- Immediate hypersensitivity (type I) -- Hypersensitivity (type II) -- Hypersensitivity (type III) -- Hypersensitivity (type IV).

Covering all the basic and clinical concepts you need to know for your coursework and USMLEs, Immunology, 9th Edition, offers a well-illustrated, carefully structured approach to this complex and fast-changing field. Carefully edited and authored by experts in both teaching and research, it provides cutting-edge, consistent coverage that links the laboratory and clinical practice. A user-friendly, color-coded format, including key concept boxes, explanatory diagrams, and nearly 200 photos to help you visually grasp and retain challenging concepts. Explains the building blocks of the immune system - cells, organs, and major receptor molecules - as well as initiation and actions of the immune response, especially in a clinical context. Includes extensive updates to clinical information, including recent clinical approaches in cancer immunology, transplantation, autoimmunity, hypersensitivity, and more. Features a reorganized format that presents immunology in the order in which is typically taught and learned, better integrating basic and clinical immunology. Covers new topics such as innate lymphoid cells, antibody-based therapies and antibody engineering, innate immunity and its components, the genetics of immunologically-based diseases and personalized medicine, and immunotherapeutic agents for the treatment of cancer. Provides Critical Thinking boxes, chapter-opening summaries, and case-based and USMLE-style questions that provide effective review and quick practice for exams - plus more learning opportunities online, including USMLE-style questions and clinical cases. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. It also features full color 3-D animations?to deliver a dynamic visual overview of immunological concepts.