000 04859cam a22003858i 4500
008 200929s2021 nju ob 001 0 eng
020 _a9781118763964
020 _a9781118764121
020 _a9781118764138
060 0 0 _aWK 100.
100 1 _aHolt, Richard I G
245 1 0 _aEssential endocrinology and diabetes
_h[E-book]
250 _a7th ed.
263 _a2103
264 1 _aHoboken, NJ :
_bJohn Wiley & Sons, Inc.,
_c2021.
300 _a1 online resource
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aEssentials
504 _aIncludes bibliographical references and index.
505 0 _aOverview of endocrinology -- Basic cell biology and hormone synthesis -- Molecular basis of hormone action -- Investigations in endocrinology and diabetes -- Hypothalamus and pituitary gland -- Adrenal gland -- Reproductive endocrinology -- Thyroid gland -- Calcium and metabolic bone disorders -- Pancreatic and gastrointestinal endocrinology and endocrine neoplasia -- Overview of diabetes -- Type 1 diabetes -- Type 2 diabetes -- Complications of diabetes -- Obesity.
520 _a"The textbook aims to be valued by different groups of reader. Its core purpose is still to provide a foundation from understanding the science to clinical training in undergraduate medicine. In addition, the content here should also be invaluable for postgraduate clinicians training in the specialty of endocrinology and diabetes. Written 'exit' examinations have become increasingly common during the later stages of clinical specialty training and we hope our textbook provides complementary study material alongside larger reference textbooks and published clinical guidelines. From feedback, we realise that our book has been valued by biomedical undergraduate and masters students and by those pursuing clinical biochemistry. We hope the new content increases this reach across different audiences. Learning objectives, recap points, cross-referencing guides, boxes, and concluding key points help orientate the reader and emphasize the major topics. Based on the success of previous editions, the book is still structured in much the same way. The first part is designed to create a knowledgeable reader, well prepared for the clinical sections or for more specific scientific study. To assist the many students coming from non-scientific backgrounds we limit assumptions on prior knowledge. Chapter 1 still covers the core principle of feedback regulation which underlies nearly all endocrine physiology and is vital for the correct interpretation of many clinical tests. Chapter 3 has advanced to encompass the latest research made possible from next generation sequencing technology. The latter has already started to impact significantly on clinical investigation and diagnostics in endocrinology and diabetes. This is covered in Chapter 4, which also includes positron emission tomography (PET) imaging. It is important that aspiring clinicians, as well as scientists, appreciate these new approaches, their application and their challenges. The second part of the book still follows its organ or system-based approach. We have retained the more specific scientific knowledge at the start of these chapters to underpin understanding, diagnosing and managing the relevant clinical disorders. The third part on diabetes and obesity has seen the greatest change from the previous edition. Over the last 8 years, there have been significant advances in the treatment of both type 2 diabetes, such as the new incretin-based therapies and SGLT2 inhibitors, and type 1 diabetes with the development of better insulins and the use of technology to support self-management. Clinical algorithms have also changed and these have been updated"--
_cProvided by publisher.
588 _aDescription based on print version record and CIP data provided by publisher; resource not viewed.
650 1 2 _aEndocrinology
_96049
650 2 2 _aDiabetes mellitus
700 1 _aHanley, Neil A
776 0 8 _iPrint version:
_aHolt, Richard I. G..
_tEssential endocrinology and diabetes
_bSeventh edition.
_dHoboken, NJ : John Wiley & Sons, Inc., 2021.
_z9781118763964
_w(DLC) 2020044319
830 0 _aEssentials (Wiley-Blackwell (Firm))
856 _uhttps://app.kortext.com/Shibboleth.sso/Login?entityID=https://idp.eng.nhs.uk/openathens&target=https://app.kortext.com/borrow/849757
_ySouth London and Maudsley Trust OpenAthens account holders click here for access
856 _uhttps://app.kortext.com/Shibboleth.sso/Login?entityID=https://idp.eng.nhs.uk/openathens&target=https://app.kortext.com/borrow/849757
_yNELFT NHS OpenAthens account holders click here for access
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_bcbc
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