| 000 | 03580cam a2200229 4500 | ||
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| 001 | 9780323550642 | ||
| 008 | 220107t2019 xxu||||| |||| 00| 0 eng d | ||
| 020 | _a9780323550642 | ||
| 020 | _a9780323479271 | ||
| 041 | _aeng | ||
| 100 | _aWallace, Daniel J. | ||
| 245 | 0 | _aDubois' lupus erythematosus and related syndromes | |
| 250 | _a9th ed. | ||
| 260 |
_aEdinburgh : _bElsevier, _c2019 |
||
| 300 | _a1 online resource (xv, 800 pages) | ||
| 505 | _aHistory of lupus -- Definition and classification of lupus and lupus-related disorders -- The epidemiology of lupus -- Overview of lupus pathogenesis -- Genetics of human SLE -- Epigenetics of lupus -- The environment and the host -- The innate immune system in SLE -- B cells and generation of antibodies -- T cells -- Adaptive and innate immunoregulatory cells -- Cytokines in lupus -- Immunometabolism -- Animal models in lupus -- Abnormalities in immune complex clearance and apoptotic cell clearance -- The role of complement in SLE -- Apoptosis and inflammatory forms of cell death -- Tissue damage in lupus : free radicals and fibrosis -- Pathogenesis of fibrosis--the lung as a model -- Pathogenesis of lupus nephritis -- Pathogenesis of accelerated atherosclerosis and vascular injury in systemic lupus erythematosus -- Pathogenesis of cutaneous lupus -- Pathogenesis of neuropsychiatric lupus -- Pathogenesis of antiphospholipid antibody syndrome -- Pathogenesis of SjoÌgren's -- Structure and derivation of autoantibodies -- Antinuclear antibodies, antibodies to DNA, histones, and nucleosomes -- Antibodies against ENA (SM, RNP, SSA, SSB) -- Antibodies against C1q -- Antilipoprotein and antiendothelial cell antibodies -- Drug-induced lupus erythematosus -- Overview and clinical presentation -- Skin disease in cutaneous lupus erythematosus -- The musculoskeletal system and bone metabolism -- Lupus and the cardiopulmonary system -- Lupus and the nervous system : clinical aspects, psychopathology, and imaging -- Gastrointestinal and hepatic systems -- Hematologic and lymphoid abnormalities in SLE -- Neonatal lupus : pathogenesis and clinical approaches -- Pregnancy and autoimmune disease, reproductive and hormonal issues -- Systemic lupus erythematosus in childhood and adolescence -- Clinical aspects of antiphospholipid syndrome -- Lupus and infections -- Ocular, aural, and oral manifestations of lupus -- Clinical aspects of SjoÌgren's -- Clinical application of serologic tests, serum protein abnormalities, and other clinical laboratory tests in systemic lupus erythematosus -- Differential diagnosis and disease associations -- Incomplete lupus, undifferentiated connective tissue disease, and mixed connective tissue disease -- Clinical markers, metrics, indices, and clinical trials -- Lupus biomarkers -- Principles of therapy, local measures, and NSAIDs -- Antimalarial medications -- Systemic glucocorticoid therapy for SLE -- Immunosuppressive drug therapy -- Complementary and alternative medications, specialized and niche therapies -- Adjunctive treatments and preventive measures -- Targeted therapies in SLE -- Management of cutaneous lupus erythematosus -- Epidemiology and management of lupus nephritis -- Management of SjoÌgren's -- Socioeconomic and disability aspects -- Prognosis and mortality of SLE." | ||
| 690 | _aSystemic lupus erythematosus. | ||
| 690 | _aLupus erythematosus. | ||
| 700 | _aHahn, Bevra | ||
| 856 | _uhttps://go.openathens.net/redirector/nhs?url=https://www.clinicalkey.com/dura/browse/bookChapter/3-s2.0-C20150067764 | ||
| 999 |
_c57539 _d57539 |
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