000 01552cam a2200217 4500
001 9780323755979
008 220107t2020 xxu||||| |||| 00| 0 eng d
020 _a9780323755979
020 _a9780323661812
041 _aeng
100 _aLee, Daniel W.
245 0 _aChimeric antigen receptor T-cell therapies for cancer: a practical guide
260 _aAmsterdam :
_bElsevier,
_c2020
300 _a1 online resource (xi, 222 pages):illustrations(chiefly color)
505 _aIntroduction -- When to refer a patient for CAR-T cell therapy -- Optimizing the apheresis product -- CAR T cells: cell processing laboratory considerations -- Peri-CAR-T cell management -- Management of cytokine release syndrome -- Special considerations for ICU management of patients receiving CAR therapy -- Neurotoxicities after CAR-T cell immunotherapy -- Hematologic and non-CRS toxicities -- Response assessment and post-CAR-T cell therapy management -- Relapse management and role for consolidative hematopoietic stem cell transplantation following CAR-T cell therapy -- Promising chimeric antigen receptors for non-B cell hematological malignancies, pediatric solid tumors, and carcinomas -- CAR T cell therapy for CNS malignancies -- CAR 2.0: the next generation of synthetic receptor-based cellular therapy for cancer.
690 _aT cells
690 _aTumor antigens.
700 _aShah, Nirali
856 _uhttps://go.openathens.net/redirector/nhs?url=https://www.clinicalkey.com/dura/browse/bookChapter/3-s2.0-C20170040661
999 _c57623
_d57623