000			05453cam a2200277 4500
001			9780323568159
008			220107t2020 xxu||||| |||| 00| 0 eng d
020			_a9780323568159
020			_a9780323476744
041			_aeng
100			_aNiederhuber, John E.
245		0	_aAbeloff's clinical oncology
250			_a6th ed.
260			_aPhiladelphia : _bElsevier, _c2020
300			_a1 online resource (xxxiii, 2037 pages):illustrations (chiefly color)
505			_aPart I: Science and clincial oncology. Section A: Biology and cancer. Molecular tools in cancer research -- Intracellular signaling -- The cellular microenvironment and metastases -- Control of the cell cycle -- The pathophysiology of cancer cell death -- Cancer immunology -- Stem cells, cell differentiation, and cancer -- Vascular and interstitial biology of tumors -- Cancer metabolism -- Section B: Genesis of cancer. Environmental factors -- DNA damage response pathways and cancer -- Viruses and human cancer -- Genetic factors: hereditary cancer predisposition syndromes -- Genetic and epigenetic changes in cancer -- Section C: Diagnosis of cancer. Pathology, biomarkers, and molecular diagnostics -- Imaging -- Section D: Clinical trials. Biostatistics and bioinformatics in clinical trials -- Trial design -- Structures supporting cancer clinical trials -- Oncology and health care policy -- Section E: Prevention and early detection. Discovery and characterization of cancer genetic susceptibility alleles -- Lifestyle and cancer prevention -- Cancer screening and early detection -- Nicotine dependence: current treatments and future directions -- Section F: Treatment. Cancer pharmacology -- Therapeutic targeting of cancer cells: era of molecularly targeted agents -- Basics of radiation therapy -- Hematopoietic stem cell transplantation -- Gene therapy in oncology -- Therapeutic antibodies and immunologic conjugates -- Complementary and alternative medicine -- Part II: Problems common to cancer and therapy -- Section A: Hematologic problems and infections. Disorders of blood cell production in clinical oncology -- Diagnosis, treatment, and prevention of cancer-related venous thrombosis -- Infection in the patient with cancer -- Section B: Symptom management. Hypercalcemia -- Tumor lysis syndrome -- Cancer-related pain -- Cancer cachexia -- Nausea and vomiting -- Section C: Treatment complications. Oral complications -- Dermatologic toxicities of anticancer therapy -- Cardiovascular effects of cancer therapy -- Reproductive complications -- Paraneoplastic neurologic syndromes -- Neurologic complications -- Endocrine complications -- Pulmonary complications of anticancer treatment -- Section D: post treatment considerations. Rehabilitation of individuals with cancer -- Survivorship -- Second malignant neoplasms -- Caring for patients at the end of life -- Section E: Local effects of cancer and its metastasis. Acute abdomen, bowel obstruction, and fistula -- Superior vena cava syndrome -- Spinal cord compression -- Brain metastases and neoplastic meningitis -- Bone metastases -- Lung metastases -- Liver metastases -- Malignancy-related effusions -- Section F: Special populations. Cancer in the elderly: biology, prevention, and treatment -- Special issues in pregnancy -- Human immunodeficiency virus (HIV) infection and cancer --;Part III: Specific malignancies. Section A: Central nervous system. Cancer of the central nervous system -- Section B: Head, neck, and eye. Ocular tumors -- Cancer of the head and neck -- Section C: Skin. Melanoma -- Nonmelanoma skin cancers: basal cell and squamous cell carcinomas -- Section D: Endocrine. Cancer of the endocrine system -- Section E: Thoracic. Cancer of the lung: non-small cell lung cancer and small cell lung cancer -- Diseases of the pleura and mediastinum -- Cancer of the esophagus and gastroesophageal junction -- Section F: Gastrointestinal. Cancer of the stomach and gastroesophageal junction -- Cancer of the small bowel -- Colon cancer -- Cancer of the rectum -- Cancer of the anal canal -- Liver and bile duct cancer -- Carcinoma of the pancreas -- Section G: Genitourinary. Cancer of the kidney -- Carcinoma of the bladder -- Prostate cancer -- Cancer of the penis -- Testicular cancer -- Section H: Gynecological. Cancers of the cervix, vulva, and vagina -- Cancer of the endometrium -- Ovaries and fallopian tubes -- Gestational trophoblastic disease -- Cancer of the breast -- Section I: Sarcomas. Sarcomas of bone -- Sarcomas of soft tissue -- Section J: Cancer of undefined site of origin. Carcinoma of Unknown Primary -- Section K: Pediatrics. Pediatric solid tumors -- Childhood leukemia -- Childhood lymphoma -- Section L: Hematological. Acute leukemias in adults -- Myelodysplastic syndromes -- Myeloproliferative disorders -- Chronic myeloid leukemia -- Chronic lymphoid leukemias -- Hairy cell leukemia -- Multiple myeloma and related disorders -- Hodgkin's Lymphoma -- Non-Hodgkin lymphoma -- Cutaneous T-cell lymphoma and cutaneous B-cell lymphoma -- Adult T-cell leukemia-lymphoma."
690			_aOncology. _913364
690			_aCancer.
700			_aArmitage, James O.
700			_aDoroshow, James H.
700			_aKastan, M.B.
700			_aTepper, Joel E.
700			_aAbeloff, Martin D.
856			_uhttps://go.openathens.net/redirector/nhs?url=https://www.clinicalkey.com/dura/browse/bookChapter/3-s2.0-C20150054004
999			_c57709 _d57709