000			04056cam a2200325 4500
001			9781119129424
008			180406t2017 xxu||||| |||| 00| 0 eng d
020			_a9781119129424
020			_a1119129427 (electronic bk.)
020			_a9781119129431 (electronic bk.)
020			_a1119129435 (electronic bk.)
020			_a(Adobe pdf)
100			_aMurphy, Michael F. (ed)
245		0	_aPractical transfusion medicine
250			_aFifth edition.
260			_aHoboken, NJ : _bJohn Wiley & Sons Inc., _c2017
300			_a1 online resource. : (electronic bk.)
500			_aPreceded by Practical transfusion medicine / edited by Michael F. Murphy, Derwood H. Pamphilon, Nancy M. Heddle. 4th ed. 2013.
505			_atext
505			_aTitle Page; Table of Contents; List of Contributors; Preface; 1 Introduction; Blood Donation Worldwide; Changing Landscape of Transfusion Risks; Immunohaematology; Clinical Use of Blood Components: Evolution Based on Evidence; Urgent Transfusion; Patients Requiring Chronic Transfusion Support; Obstetric, Neonatal and Paediatric Transfusion Medicine; Haemostasis and Transfusion; Cellular Therapies, Transplantation, Apheresis; The Future; Conclusion; References; Part I: Basic Principles of Immunohaematology; 2 Essential Immunology for Transfusion Medicine; Cellular Basis of the Immune Response
505			_aB‐Cell Activation and T‐Cell‐Dependent Antibody FormationHumoral Immune Response; Antibody Effector Functions; Red Blood Cell Antibodies Illustrating the Above Principles; Antibody and Complement‐Mediated Blood Cell Destruction; Clinical Aspects Related to Alloimmunisation Against Blood Cell Antigens; References; Further Reading; 3 Human Blood Group Systems; Introduction; The ABO System; The Rh System; Other Blood Group Systems; Biological Significance of Blood Group Antigens; References; Further Reading; 4 Human Leucocyte Antigens; Introduction; HLA Class I Genes; HLA Class II Genes
505			_aGenetic Organisation and Expression of HLA Class II GenesExpression of HLA Molecules; Genetics; Function of HLA Molecules; Identification of HLA Gene Polymorphism; Formation of HLA Antibodies; Detection of HLA Antibodies; Clinical Relevance of HLA Antigens and Antibodies; HLA and Disease; References; Further Reading; 5 Platelet and Neutrophil Antigens; Antigens on Platelets and Granulocytes; Human Platelet Antigens; Human Neutrophil Antigens; References; Further Reading; 6 Pretransfusion Testing and the Selection of Red Cell Products for Transfusion; Introduction
505			_aDetermining the Recipient's ABO Group and Screening for Unexpected AntibodiesCrossmatching Techniques; Selection of Red Cells for Transfusion; Selection of Platelets and Plasma Components; References; Further Reading; Part II: Complications of Transfusions; 7 Investigation of Acute Transfusion Reactions; Introduction; Understanding the Clinical Presentation and Differential Diagnosis; General Approach for Investigation and Treatment of Acute Transfusion Reactions; Algorithm; References; Further Reading; 8 Haemolytic Transfusion Reactions; Definition of a Haemolytic Transfusion Reaction
505			_aPathophysiology of HTRsAcute HTRs; Delayed HTRs; Acute Haemolysis from ABO‐Incompatible Platelet Transfusions; References; Further Reading; 9 Febrile and Allergic Transfusion Reactions; Introduction; Febrile Non‐haemolytic Transfusion Reactions; Allergic Transfusion Reactions; References; 10 Lung Injury and Pulmonary Oedema After Transfusion; Definition; Incidence, Outcomes and Recipient Risk Factors; Clinical Manifestations; Differential Diagnosis; Pathogenesis; Lung Histology; Types of Blood Components That Can Cause TRALI; Mitigation Strategies; Patient Management; References
520			_aRemote
520			_aIncludes bibliographical references and index.
700			_aRoberts, David J. [(Consultant hematologist),] (ed)
700			_aYazer, Mark H. (ed)
856			_uhttp://dx.doi.org/10.1002/9781119129431 _y[Wiley Online Library]
999			_c58259 _d58259