| 000 | 05368cam a2200217 4500 | ||
|---|---|---|---|
| 001 | NMDX6628 | ||
| 008 | 120401t2009 xxu||||| |||| 00| 0 eng d | ||
| 022 | _a01443615 | ||
| 100 | _aFleischmann, G. | ||
| 240 | _aJournal of Obstetrics and Gynaecology | ||
| 245 | _aDemographics and outcome of elective cerclage in a multi-ethnic London district general hospital | ||
| 260 | _c2009 | ||
| 500 | _aNMUH Staff Publications | ||
| 500 | _a29 | ||
| 520 | _a<span style="font-size: 8pt;"><span class="highlight" style="line-height: 17.999801635742188px;">Elective</span><span style="line-height: 17.999801635742188px;">&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">cerclage</span><span style="line-height: 17.999801635742188px;">&nbsp;is a rare procedure, but is reported to be relatively more common in developing countries. This variation in rate may be reflected in a&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">multi-ethnic</span><span style="line-height: 17.999801635742188px;">&nbsp;population as seen in&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">London</span><span style="line-height: 17.999801635742188px;">. Our study analysed the epidemiology and rate of&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">elective</span><span style="line-height: 17.999801635742188px;"></span><span class="highlight" style="line-height: 17.999801635742188px;">cerclage</span><span style="line-height: 17.999801635742188px;">&nbsp;performed in a&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">London</span><span style="line-height: 17.999801635742188px;">&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">district</span><span style="line-height: 17.999801635742188px;">&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">general</span><span style="line-height: 17.999801635742188px;">&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">hospital</span><span style="line-height: 17.999801635742188px;">. Factors contributing to the&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">outcome</span><span style="line-height: 17.999801635742188px;">&nbsp;of the procedures were also reviewed. A total of 41&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">elective</span><span style="line-height: 17.999801635742188px;">&nbsp;cerclages were performed in the&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">hospital</span><span style="line-height: 17.999801635742188px;">&nbsp;between 2000 and 2007. Data from these were collected retrospectively, including maternal history, operative details, and gestational age at delivery. Fisher's exact test was used for statistical analysis. Of the 41 cases, 19 pregnancies were carried to term (&gt;or=37 weeks' gestation), nine were pre-term (24-36 weeks' gestation) and seven miscarried (&lt;24 weeks' gestation); six cases had not yet delivered. All of the patients were immigrants from developing countries but ethnicity did not affect the operative&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">outcome</span><span style="line-height: 17.999801635742188px;">&nbsp;(p = 0.89, Fisher's exact). The other factors studied were also noted to have no significant impact on success. These included cervical length at insertion (p = 1.00, Fisher's exact), type of suture (p = 0.90, Fisher's exact) and average gestation at insertion (p = 0.20, Fisher's exact). In conclusion, all patients requiring intervention in this study originated from developing countries. This is a disproportionately high figure relative to the demographic breakdown of the study population. Such a finding may be due to geographical variation of risk factors for cervical incompetence but may also be influenced by observer bias. Additional studies are needed to further investigate the influence of ethnicity on the rate of&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">elective</span><span style="line-height: 17.999801635742188px;">&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">cerclage</span><span style="line-height: 17.999801635742188px;">. None of the variables analysed in this study significantly affected the&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">outcome</span><span style="line-height: 17.999801635742188px;">&nbsp;of the procedure.</span></span> | ||
| 700 | _aSteel, A. | ||
| 700 | _aYoong, W. | ||
| 700 | _aFakokunde, A. | ||
| 856 | _uhttp://informahealthcare.com/doi/pdf/10.1080/01443610802628809 | ||
| 856 | _uwww.ncbi.nlm.nih.gov/pubmed/19280489 | ||
| 999 |
_c75785 _d75785 |
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