000			03177cam a2200229 4500
001			1405133945
008			150528t2007 xxu||||| |||| 00| 0 eng d
020			_a1405133945
020			_a9781405133944 (alk. paper)
100			_aDzau, Victor J. (ed)
245		0	_aCardiovascular genetics and genomics for the cardiologist
260			_aMalden, Mass. _bBlackwell Futura _c2007
300			_axi, 308 p. : ill.
505			_aThe gene in the twenty-first century / Choong-Chin Liew, Victor J. Dzau -- Monogenic hypercholesterolemia / Ruth McPherson -- Hypertrophic cardiomyopathy / Ali J. Marian -- Dilated cardiomyopathy and other cardiomyopathies / Mitra Esfandiarei, Robert Yanagawa, Bruce M. McManus -- The long QT syndrome / Sabina Kupershmidt, Kamilla Kelemen, Tadashi Nakajima -- Atherosclerosis / Päivi Pajukanta, Kiat Tsong Tan, Choong-Chin Liew -- Heart failure / Markus Meyer, Peter VanBuren -- The implications of genes on the pathogenesis, diagnosis, and therapeutics of hypertension / Kiat Tsong Tan, Chong-Chin Liew -- Gene therapy for cardiovascular disease: inserting new genes, regulating the expression of native genes, and correcting genetic defects / Ion S. Jovin, Frank J. Giordano -- Stem cell therapy for cardiovascular disease / Emerson C. Perin, Guilherme V. Silva -- Pharmacogenetics and personalized medicine / Julie A. Johnson, Issam Zineh -- The potential of blood-based gene profiling for disease assessment / Steve Mohr, Choong-Chin Liew.
520			_aIncludes bibliographical references and index.
520			_aUntil recently, a modest knowledge of genetics was more than adequate for the daily practice of clinical cardiology, but advances in genetics and genomics are changing cardiovascular medicine in fundamental ways. The identification of the genetic basis of several forms of dyslipidemia, hypertension, diabetes, cardiomyopathies, and vascular diseases signalled the new importance of genetics in clinical medicine. In this timely volume, Drs. Dzau and Liew - both pioneers in the area - help cardiologists understand: * how cardiovascular genetics may remodel the way cardiovascular medicine is practiced * what material has immediate relevance to the practicing clinician * how to incorporate genetics and genomics in your practice to ensure up-to-date patient care The book opens with introductory chapters, then discusses cardiovascular single gene disorders, cardiovascular polygenic disorders, therapies and applications. Outstanding contributors write on their areas of expertise, making Cardiovascular Genetics and Genomics for the Cardiologist both authoritative and comprehensive. If you want to gain a better appreciation of how genetics and genomics are already shaping current practice and may potentially revolutionize cardiology, look no further than this dependable reference.
650			_aCARDIOVASCULAR DISEASES, genetics
650			_aCARDIOVASCULAR DISEASES, therapy
700			_aLiew, Choong-Chin (ed)
856			_uhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&NEWS=n&CSC=Y&PAGE=booktext&D=books&AN=01435150$&XPATH=/PG(0) _y[ebook. Login with your Homerton OpenAthens username and password.]
999			_c86000 _d86000