000			02145aam a22002291a 4500
008			140314s2014 flu o 000 0 eng d
020			_a9781439873670
020			_a9781439873700 (ebk)
020			_a9781306136891
060			_aWX 175
100	1		_aCappelleri, Joseph C., _eauthor
245	1	0	_aPatient-reported outcomes : _bmeasurement, implementation and interpretation _h[E-book]
260			_aBoca Raton, Florida : _bChapman and Hall/CRC, _c2014
490	0		_aChapman & Hall/CRC biostatistics series
520			_aAdvancing the development, validation, and use of patient-reported outcome (PRO) measures, Patient-Reported Outcomes: Measurement, Implementation and Interpretation helps readers develop and enrich their understanding of PRO methodology, particularly from a quantitative perspective. Designed for biopharmaceutical researchers and others in the health sciences community, it provides an up-to-date volume on conceptual and analytical issues of PRO measures. The book discusses key concepts relating to the measurement, implementation, and interpretation of PRO measures. It covers both introductory and advanced psychometric and biostatistical methods for constructing and analyzing PRO measures. The authors include many relevant real-life applications based on their extensive first-hand experiences in the pharmaceutical industry. They implement a wealth of simulated datasets to illustrate concepts and heighten understanding based on practical scenarios. For readers interested in conducting statistical analyses of PRO measures and delving more deeply into the analytic details, most chapters contain SAS code and output that illustrate the methodology. Along with providing numerous references, the book highlights current regulatory guidelines.
650		4	_aStatistics _97992
650		0	_aBiostatistics
650		4	_aPatient participation _97347
650		4	_aOutcome assessment _97281
856			_uhttps://app.kortext.com/Shibboleth.sso/Login?entityID=https://idp.eng.nhs.uk/openathens&target=https://app.kortext.com/borrow/86953 _yNELFT NHS OpenAthens account holders click here for access
942			_n0
999			_c89260 _d89260