000			05365cam a2200661Ia 4500
001			ocn261137374
003			OCoLC
005			20221128211136.0
006			m d
007			cr cnu---unuuu
008			081007s2008 njua ob 001 0 eng d
040			_aN$T _beng _epn _cN$T _dOCLCQ _dIDEBK _dE7B _dOCLCQ _dOCLCA _dM6U _dOCLCF _dOCLCA _dNLGGC _dYDXCP _dOCLCQ _dSTF _dOCLCQ _dD6H _dAGLDB _dOCLCO _dJBG _dOCLCO _dTOA _dOCLCO _dVTS _dREC _dTOF _dM8D _dOCLCO _dUKAHL _dOCLCA _dOCLCO
019			_a646768927 _a696628363
020			_a9789812819178 _q(electronic bk.)
020			_a9812819177 _q(electronic bk.)
020			_z9789812705365
020			_z9812705368
020			_z9789812705372 _q(pbk.)
020			_z9812705376 _q(pbk.)
035			_a236114 _b(N$T)
035			_a(OCoLC)261137374 _z(OCoLC)646768927 _z(OCoLC)696628363
060		4	_aQU 55 N736 2008
072		7	_aMED _x067000 _2bisacsh
072		7	_aMED _x068000 _2bisacsh
049			_aMAIN
100	1		_aKumar, Rakesh _c(Professor of Biotechnology)
245	1	0	_aNR coregulators and human diseases _c _h[E-Book]
260			_aHackensack, N.J. : _bWorld Scientific, _c2008.
300			_a1 online resource (xi, 602 pages) : _billustrations
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
504			_aIncludes bibliographical references and index.
505	0		_aNuclear receptor coregulators in human disease / Rainer B. Lanz, David M. Lonard, and Bert W. O'Malley -- P160 coactivators : critical mediators of transcriptional activation by nuclear receptors / Jeong Hoon Kim and Michael R. Stallcup -- Regulation of nuclear hormone receptor functions by ubiquitin-proteasome pathway / Ayesha Ismail, Heath Catoe, Sarath Dhananjayan, and Zafar Nawaz -- Coregulators as oncogenes and tumor suppressors / Rakesh Kumar and Anupama E. Gururaj -- A central role of SRC-3/AIB1 in tumorigenesis / Jun Yan, Sophia Y. Tsai, and Ming-Jer Tsai -- Thyroid hormone receptors, coregulators, and disease / Martin L. Privalsky -- Androgen receptor coactivators in prostate cancer / Nancy L. Weigel and Irina U. Agoulnik -- PGC-1 and metabolic control in skeletal and cardian muscle / Zolt Arany and Bruce M. Spiegelman -- Coregulators in metabolic and neurodegenerative diseases / J�er�ome N. Feige, Hiroyasu Yamamoto, and Johan Auwerx -- Role of the RIP140 corepressor in metabolic regulation / Malcolm G. Parker, Mark Christian, Evangelos Kiskinis, Asha Seth, Donna Nichol, and Roger White -- Nuclear receptor corepressors and metabolism / Theresa Alenghat and Mitchell A. Lazar -- Coregulators in CNS functions and disease / O.C. Meijer and E.R. de Kloet -- Tissue repair and cancer control through PPARs and their coregulators / Liliane Michalik and Walter Wahli -- Coregulators and inflammation / Serena Ghisletti, Wendy Huang, and Christopher K. Glass -- Nuclear receptor coactivators in the cardiovascular system / Jianming Xu -- Coregulators as determinants of Selective Receptor Modulator (SRM) activity / Margaret C. Pace and Carolyn L. Smith -- Coregulators in toxicology / Jo�egg, Malin Hedengran-Gaulds, Manuela Hase, Ingemar Pongratz and Jan-�Ake Gustafsson -- Nuclear receptor coactivators co-ordiante metabolic response to hormonal and environmental stimuli / Ronald M. Evans, Michael Downes, Russell R. Nofsinger, Jun Sonoda and Ruth T. Yu -- Nuclear receptor cofactor interactions as targets for new drug discover / Linda L. Grasfeder and Donald P. McDonnell.
588	0		_aPrint version record.
520			_aThis book serves as a treasure for all those who have an interest in nuclear receptor coregulators and human diseases. Written by experts in the field, each chapter provides comprehensive, up-to-date information on the physiologic and pathologic roles of coregulators in specific organ systems, giving biomedical students; basic and clinical researchers; and educators in diverse sub-specialties a thorough summary of the overall subject. Readers will be able to understand the important current information and views on specific coactivators and corepressors and their roles in the pathogenesis of human diseases in areas outside their own expertise or experience. A special emphasis is placed on the "classic" papers as well as perspectives on future directions for the field.
590			_aWorldCat record variable field(s) change: 650
650		0	_aPathology, Molecular.
650		0	_aNuclear receptors (Biochemistry)
650		0	_aGenetic regulation.
650		0	_aTranscription factors.
650		0	_aGenetic transcription.
650	1	2	_aReceptors, Cytoplasmic and Nuclear
650	1	2	_aPathology
650	2	2	_aGene Expression Regulation
650	2	2	_aDNA _xmetabolism
650	2	2	_aTranscription Factors
650	2	2	_aTranscription, Genetic
650		2	_aPathology, Molecular
700	1		_aO'Malley, Bert W.
856	4	0	_uhttps://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=236114 _yKingston Hospital NHS Foundation Trust OpenAthens account holders click here for access
938			_aAskews and Holts Library Services _bASKH _nAH24685943
938			_aebrary _bEBRY _nebr10255916
938			_aEBSCOhost _bEBSC _n236114
938			_aYBP Library Services _bYANK _n2889378
942			_n0
994			_a92 _bN$T
999			_c89528 _d89528