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020 _a0470187913
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024 7 _a10.1002/9780470187920
_2doi
035 _a267551
_b(N$T)
035 _a(OCoLC)608623827
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037 _a10.1002/9780470187920
_bWiley InterScience
_nhttp://www3.interscience.wiley.com
060 4 _a2007 M-292
060 4 _aQV 38
_bD7916 2008
072 7 _aMED
_x071000
_2bisacsh
049 _aMAIN
245 0 0 _aDrug-drug interactions in pharmaceutical development
_c
_h[E-Book]
260 _aHoboken, N.J. :
_bWiley-interscience,
_c2008.
300 _a1 online resource (xiv, 244 pages, [1] pages) :
_billustrations (some color)
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _adata file
_2rda
490 1 _aWiley series in drug discovery and development
504 _aIncludes bibliographical references and index.
505 0 _aIn vitro evaluation of metabolic drug-drug interactions: concepts and practice / Albert P. Li -- In vitro approaches to anticipating clinical drug interactions / Laurie P. Volak, David J. Greenblatt, Lisa L. von Moltke -- Inhibition of drug metabolizing enzymes and drug-drug interactions in drug discovery and development / R. Scott Obach -- Mechanism-based CYP inhibition: enzyme kinetics, assays, and prediction of human drug-drug interactions / Magang Shou -- Genomic approaches to drug-drug interactions / Yi Yang, Jeffrey F. Waring -- Transporters and drug interactions / Yoshihisa Shitara, Toshiharu Horie, and Yuichi Sugiyama -- Transporter-mediated drug interactions: molecular mechanisms and clinical implications / Jiunn H. Lin -- Recent case studies of clinically significant drug-drug interactions and the limits of in vitro prediction methodology / R.H. Levy, I. Ragueneau-Majlessi, C. Collins -- US regulatory perspective: drug-drug interactions / John Strong and Shiew-Mei Huang -- Herbal drug interactions: a Canadian perspective / Brian C. Foster.
588 0 _aPrint version record.
520 _aDrug-Drug Interactions in Pharmaceutical Development comprehensively reviews the relevant science, industrial practice, and regulatory agency positions on drug-drug interactions. It focuses on the evaluation of potential drug-drug interactions, allowing researchers to address risk factors before a drug is put to market. The book covers both clinical and nonclinical aspects for understanding drug-drug interactions as well as in vitro and in vivo studies for use in studying interactions at the drug discovery stage.
546 _aEnglish.
590 _aWorldCat record variable field(s) change: 650
650 0 _aDrug interactions.
_95955
650 0 _aDrug development.
650 0 _aPharmaceutical chemistry.
650 1 2 _aDrug Interactions
_95955
650 2 2 _aChemistry, Pharmaceutical
700 1 _aLi, A. P.
830 0 _aWiley series in drug discovery and development.
856 4 0 _uhttps://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=267551
_yKingston Hospital NHS Foundation Trust OpenAthens account holders click here for access
938 _a123Library
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938 _aEBSCOhost
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938 _aProQuest MyiLibrary Digital eBook Collection
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938 _aYBP Library Services
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938 _aYBP Library Services
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