000			04958cam a2200589 i 4500
001			ocn952772313
003			OCoLC
005			20221128211659.0
006			m d
007			cr |||||||||||
008			110322s2011 nyua ob 001 0 eng
010			_a 2019714320
040			_aDLC _beng _erda _cDLC _dUMMBL _dOCLCO _dN$T _dYDXCP _dOCLCF _dNLGGC _dD6H _dMERUC _dAGLDB _dZCU _dVTS _dCOCUF _dTOF _dAU@ _dWYU _dREC _dVT2 _dSTF _dK6U
016	7		_a015875048 _2Uk
019			_a779844104 _a1066598908 _a1081262926
020			_a9781620810453 _qebook
020			_a162081045X
020			_z1613244444 _qhardcover : alk. paper
020			_z9781613244449 _qhardcover : alk. paper
035			_a439182 _b(N$T)
035			_a(OCoLC)952772313 _z(OCoLC)779844104 _z(OCoLC)1066598908 _z(OCoLC)1081262926
060	1	0	_aQW 805
072		7	_aMED _x071000 _2bisacsh
049			_aMAIN
245	0	0	_aDNA vaccines : _btypes, advantages, and limitations _c _h[E-Book]
264		1	_aNew York : _bNova Biomedical Books, _cc2011.
300			_a1 online resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	1		_aImmunology and immune system disorders
504			_aIncludes bibliographical references and index.
588			_aDescription based on print version record.
505	0		_aDNA VACCINES: TYPES, ADVANTAGES AND LIMITATIONS ; IMMUNOLOGY AND IMMUNE SYSTEM DISORDERS ; DNA VACCINES: TYPES, ADVANTAGES AND LIMITATIONS ; Contents ; Preface ; Novel Carrier Adjuvant for DNA Vaccination ; Abstract ; 1. Introduction ; 2. Immunology of DNA Vaccines: Mode of Action and Immune Response Induction ; 3. Barriers in DNA Vaccine Delivery and Possible Modes to Overcome these Barriers ; 4. Novel Strategies for DNA Delivery ; 4.1. Lipid Based Carrier Adjuvants for DNA Vaccination ; 4.1.1. Liposomes ; 4.1.2. Virosomes.
505	8		_a4.2. Polymers and Polymeric Carriers Systems 4.2.1. Polyethylenimine ; 4.2.2. Polylysine ; 4.2.3. Chitosan ; 4.2.4. Dendrimers ; 5. Concluding Remark and Future Prospects ; References ; Improving the Immunogenicity of DNA Vaccines: A Nano-Sized Task? ; Abstract ; Introduction ; Improving Immunogenicity of Plasmid DNA Vaccines ; Routes of Delivery of Plasmid DNA Vaccines ; Physical Delivery Systems of Plasmid DNA Vaccines ; Needle-Free Delivery Methods ; Expression Optimization ; Cytokines ; Delivery Vectors for DNA Vaccines ; Bacterial Vectors ; Viral Vectors.
505	8		_aDNA and RNA Replicons Nano-Sized Vehicles for Gene Delivery ; Inorganic to Biomaterial -- Past to Future ; Size Determines the Fate of Particles ; Conclusion ; References ; Novel Delivery Strategies for DNA ; Abstract ; I. Introduction ; II. Optimization of Immunogenicity of DNA Vaccines ; 2.1. Choice of Targets and Expression Plasmid for DNA Vaccines ; 2.2. Selection of High Expression Plasmids for DNA Vaccines ; 2.3. Codon Optimization for Higher Gene Expression ; 2.4. Adjuvant Choice for DNA Vaccines ; III. DNA Delivery Strategies ; 3.1. Invasive Delivery.
505	8		_a3.1.1. Needle Injection 3.1.2. In Vivo Electroporation ; 3.1.3. Tattoo Gun Delivery ; 3.2. Non-Invasive Topical Delivery Method ; 3.2.1. Tape Stripping ; 3.2.2. Nanopatch Delivery ; 3.2.3. Nano-Particle Mediated Delivery ; 3.3. Viral-Mediated DNA Delivery Systems ; 3.4. Non-Viral Gene Delivery Systems ; 3.5. Novel Delivery Methods ; 3.5.1. Laser Mediated Delivery ; 3.5.2. Ultrasound Mediated Delivery System ; III. Future Directions ; References ; Recent Advances in DNA Vaccines ; Abstract ; Introduction ; DNA Vaccines X Traditional Vaccine Approaches ; Components of a DNA Vaccine.
505	8		_aHow DNA Vaccines Work Delivery Methods ; Advantages X Limitations ; Strategies to Enhance Immunogenicity of DNA Vaccines ; Modifications of Plasmid Basic Design ; Delivery Methods ; Target to Dendritic Cells ; Improved Immunization Protocols ; Adjuvants ; Conclusion ; References ; Co-Administration of Gamma Interferon Gene with DNA Vaccine Expressing Duck Hepatitis B Virus (DHBV) Proteins Enhances Therapeutic Efficacy of DNA-Based Immunization in Chronic Virus Carriers ; Abstract ; Introduction ; Materials and Methods ; Animals ; DNA Immunization.
590			_aMaster record variable field(s) change: 072 - OCLC control number change
650		0	_aDNA vaccines.
650		2	_aVaccines, DNA.
700	1		_aDonnelly, Erin C.
700	1		_aDixon, Arthur M.
830		0	_aImmunology and immune system disorders.
856	4	0	_uhttps://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=439182 _yKingston Hospital NHS Foundation Trust OpenAthens account holders click here for access
938			_aProQuest Ebook Central _bEBLB _nEBL3021072
938			_aebrary _bEBRY _nebr10681272
938			_aEBSCOhost _bEBSC _n439182
938			_aYBP Library Services _bYANK _n7561576
942			_n0
994			_a92 _bN$T
999			_c90302 _d90302