000 05769nam a2200481Ka 4500
001 ocn848918183
003 OCoLC
005 20221128211959.0
006 m d
007 cr cnu---unuuu
008 130617s2013 enka ob 001 0 eng d
040 _aN$T
_cN$T
020 _a9781139840019 (electronic bk.)
020 _a1139840010 (electronic bk.)
020 _z9781107012134
020 _z1107012139
035 _a(OCoLC)848918183
035 _a498332
_b(N$T)
060 1 4 _aWQ 211
_bF41997 2013
072 7 _aMED
_x070000
_2bisacsh
049 _aN$TA
245 0 0 _aFetal therapy
_h[electronic resource] :
_bscientific basis and critical appraisal of clinical benefits
_c
260 _aCambridge :
_bNew York :
_bCambridge University Press,
_c2013 .
300 _a1 online resource (xv, 453 p.) :
_bill. (chiefly col.).
490 1 _aCambridge medicine
504 _aIncludes bibliographical references and index.
505 8 _aMachine generated contents note: Preface; Foreword; Part I. General Principles: 1. The rationale for fetal therapy; 2. Insights into pathogenesis of adult cardiovascular disease from fetal animal studies; 3. Human embryology: molecular mechanisms of embryonic disease; 4. Ethics of fetal therapy; 5. Fetal therapy choices: about risks, emotions, and the doctor's role in the decision making process; Part II. Fetal Disease: Pathogenesis and Principles: 6. Red cell alloimmunization: immunobiology, clinical disease, and management; 7. Fetal and neonatal alloimmune thrombocytopenia; 8.1. Fetal dysrhythmias: the effects of antiarrhythmic therapy on the immature heart; 8.2. Fetal dysrhythmias: clinical management; 9.1. Structural heart disease: embryology; 9.2. Structural heart disease: genetic influences; 9.3. Structural heart disease: fetal cardiac interventions; 10.1. Manipulation of amniotic fluid volume: homeostasis of fluid volumes in the amniotic cavity; 10.2. Manipulation of amniotic fluid volume: oligohydramnios and polyhydramnios; 11.1. Twin-to-twin transfusion syndrome: scientific basis; 11.2. Twin-to-twin transfusion syndrome: placental circulation; 11.3. Twin-to-twin transfusion syndrome: cardiovascular manifestations; 11.4. Twin-to-twin transfusion syndrome: treatment by fetoscopic laser ablation; 11.5. Twin-to-twin transfusion syndrome: management of stage I disease; 12.1. Twin reverse arterial perfusion (TRAP) sequence: pathophysiology; 12.2. Twin reverse arterial perfusion (TRAP) sequence: in-utero treatment; 13.1. Fetal infections: fetal immune responses to congenital infections; 13.2. Fetal infections: clinical management; 14.1. Fetal urinary tract obstruction: pathophysiology; 14.2. Fetal urinary tract obstruction: prenatal assessment and prognosis; 14.3. Fetal urinary tract obstruction: fetal cystoscopy; 14.4. Fetal urinary tract obstruction: in-utero intervention; 15.1. Fetal lung growth, development and lung fluid: physiology and pathophysiology; 15.2. Fetal lung growth, development, and lung fluid: clinical management of pleural effusion and pulmonary pathology; 16.1. Neural tube defects: pathophysiology and prevention; 16.2. Neural tube defects: clinical management; 17.1. Fetal tumors: pathophysiology; 17.2. Fetal tumors: clinical management; 18.1. Intrauterine growth restriction: placental basis and implications for clinical practice; 18.2. Intrauterine growth restriction: differential diagnosis and management; 19.1. Congenital diaphragmatic hernia: pathophysiology; 19.2. Congenital diaphragmatic hernia: clinical antenatal management; 20.1. Fetal stem cell transplantation: stem cell biology basics; 20.2. Fetal stem cell transplantation: clinical potential; 20.3. Fetal stem cell transplantation: fetal tissue engineering; 21. Gene therapy: physiological principles and clinical potential; 22. The future: fetal therapies and translation studies: global alignment, coordination and collaboration in perinatal research: The Global Obstetrics Network (GONet) initiative; Index.
520 _a"Fetal treatment, particularly complex fetal therapy, is an emergent and expanding field. This comprehensive text focuses on areas of fetal disease and pathophysiology that can be treated in utero and the benefits and problems with such therapy. Both medical (non-invasive) and surgical procedures are discussed, drawing on the expertise of an internationally renowned author team. Each chapter includes a comprehensive overview of the basic science underlying fetal pathology, as well as discussing the highest level of technical performance of fetal interventions. Contributions from fetal therapy 'centers-of-excellence' around the world collectively emphasize the need for an evidence-based approach to the field. This volume is useful both as a quick reference guide to the latest fetal therapy options and as an in-depth study book for maternal-fetal medicine and neonatology specialists at any stage of their career who are seeking to acquire essential background knowledge. Indispensable on any bookshelf in fetal medicine units"--Provided by publisher.
588 _aDescription based on print version record.
650 0 _aFetus
_xDiseases.
650 1 2 _aFetal Diseases
_xtherapy.
650 2 2 _aFetal Stem Cells
_xtransplantation.
650 2 2 _aFetal Therapies
_xmethods.
700 1 _aKilby, Mark.
700 1 _aJohnson, Anthony,
_d1954-
700 1 _aOepkes, Dick.
830 0 _aCambridge medicine.
856 4 0 _uhttps://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=498332
_yKingston Hospital NHS Foundation Trust OpenAthens account holders click here for access
938 _aEBSCOhost
_bEBSC
_n498332
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