000			08484cam a2200721 a 4500
001			ocn834136823
003			OCoLC
005			20221128212120.0
006			m d
007			cr cnu---unuuu
008			130401s2012 gw ob 001 0 eng d
040			_aN$T _beng _epn _cN$T _dCOO _dOCLCO _dE7B _dYDXCP _dCUS _dOCLCF _dOCLCO _dIDEBK _dOCLCQ _dOCLCO _dEBLCP _dOCLCQ _dOCLCO _dD6H _dOCLCO _dAGLDB _dOCLCQ _dIGB _dJBG _dOCLCO _dOCLCA _dVTS _dAU@ _dSTF _dOCLCQ _dAJS _dOCLCO _dOCLCA _dTHIEM _dOCLCA _dOCLCQ _dOCLCO
019			_a827468088 _a852758516
020			_a9783131645715 _q(electronic bk.)
020			_a3131645717 _q(electronic bk.)
020			_a9781283638838 _q(MyiLibrary)
020			_a1283638835 _q(MyiLibrary)
020			_z9783131473912
020			_z3131473916
035			_a534251 _b(N$T)
035			_a(OCoLC)834136823 _z(OCoLC)827468088 _z(OCoLC)852758516
037			_a395129 _bMIL
060		4	_aWE 707
072		7	_aRC _2lcco
072		7	_aHEA _x039030 _2bisacsh
072		7	_aMED _x062000 _2bisacsh
049			_aMAIN
245	0	0	_aHead and neck cancer recurrence : _bevidence-based, multidisciplinary management _c _h[E-Book]
260			_aStuttgart : _bThieme, _c2012.
300			_a1 online resource (xi, 304 pages)
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
504			_aIncludes bibliographical references and index.
520			_a"Over the past 5 to 10 years, organ preservation techniques using chemoradiotherapy have gained considerable popularity as first-line treatment of head and neck cancer, especially for oropharyngeal, laryngeal, and hypopharyngeal cancer. This trend is now increasing with more intensified chemoradiotherapy treatment modalities and regimens. This means that more and more advanced disease is likely to be treated with chemoradiotherapy as a primary treatment, with increased likelihood of failure of these treatments (almost half of the patients relapse, but the organ-preserving aspect of chemoradiotherapy makes it in many cases so very worthwhile as a primary treatment). As chemoradiotherapy is a relatively new management philosophy, experience of salvaging patients with recurrences is therefore still relatively limited and expertise of it is not yet highly developed, although it is an area of great interest for the wider specialties involved. This book is specifically compiled to provide evidence-based, multidisciplinary management strategies for this complex and difficult to manage disease, combined with an account of the relevant techniques, results, and possible complications that might arise and how to deal with them. The book is intended for practicing specialists in head and neck cancer both surgery and oncology. It is aimed at the consultant level as well as at senior trainees interested in the field. Special features: Evidence-based, comprehensive review of the topic, which is very difficult to deal with in clinical practice and poorly covered in the literature International, multidisciplinary authorship including the top clinicians in their fields; most chapters have a surgeon and an oncologist involved, which offers top expertise and a balanced, multidisciplinary view General chapters on principles of relevant surgical p techniques and radiotherapy; site-specific chapters dealing with specific management of recurrence at each head and neck site Pactical tips and pitfalls sections the practical details will allow readers to improve patient management and outcomes Illustrative cases including history, clinical findings, imaging, treatment (incl. Plplanning and results) brings decision-making process to life and easier to relate to clinical practice Summaries, recommended further reading and further research sections highlight important aspects, offer a valuable reference facility, and point out specific needs for further systematic studiesTarget groups: head and neck surgeons (with a background in otolaryngology, maxillofacial surgery, or plastic surgery), head and neck radiation and medical oncologists"--Provided by publisher
520			_a"The only book dedicated to provide evidence-based management strategies for this complex and difficult to manage recurrant disease, complied by an international, multidisciplinary group of the world's top experts in the field of head and neck cancer"--Provided by publisher
588	0		_aPrint version record.
505	0		_aHead and Neck Cancer Recurrence: Evidence-based, Multidisciplinary Management; Title Page; Copyright; Contributors; Preface; Acknowledgments; Contents; 1 Introduction; Clinical Assessment and Imaging Evaluation of Recurrence; Principles of the Assessment of Potential Recurrence; History and Examination; Previous Treatment Records; Imaging; Examination under Anesthetic; Needle or Open Biopsy; 2 Molecular Biology of Recurrence; Introduction; The Biology of Treatment Resistance; Activation of Alternative Signaling Pathways; Biological Processes Involved in Metastasis; Conclusions.
505	8		_a3 Imaging Modalities for Head and Neck Cancer RecurrenceTherapy-related Changes in the Head and Neck Region; Imaging Modalities for Detection of Recurrence; Imaging for Recurrence at Specific Sites; 4 Concurrent Chemotherapy and Re-irradiation for Recurrent Head and Neck Cancer; Introduction; Reasons for Tumor Recurrence Following Definitive Therapy; Regimens for Concurrent Chemotherapy with Re-irradiation; Evidence for Concurrent Chemotherapy with Re-irradiation; Brachytherapy for Recurrent Head and Neck Cancer; Patient Selection and Prognostic Factors.
505	8		_aSimulation and Planning for Re-irradiationTreatment Volume Definition; Beam Arrangement; Advances in Delivery of Radiation; New Approaches to CRRT; Conclusion; 5 Systemic Therapy in the Treatment of Recurrent and Metastatic Head and Neck Carcinoma; Patient's Clinical Profile and Assessment; Clinical Decision Making; Medical Treatment; Special Issues in End-of-Life Supportive Care; 6 Principles and Concepts of Reconstruction in the Recurrent Setting; Introduction; Issues in Surgical Approach-Impact of Previous Treatment; Management of the Vessel-depleted Neck.
505	8		_aSite-specific Defect ConsiderationsConclusion; 7 Patient Selection for Treatment; Introduction; Assessment of the Recurrent Cancer; Factors Involved in Treatment Selection; Involving the Patient in the Decision-making Process; Treatment Options; 8 Recurrent Laryngeal Cancer; Introduction; Epidemiology; Diagnosis of Recurrent Laryngeal Cancer; Staging of Recurrent Laryngeal Cancer; Principles of Management; Surgical Management of Recurrent Disease; 9 Management of Recurrent Hypopharyngeal Cancer; Incidence and Patterns of Recurrence in Hypopharyngeal Cancer; Detection of Recurrent Disease.
505	8		_aPrinciples of ManagementSurgical Techniques of Salvage Pharyngolaryngectomy; Re-irradiation for Recurrent Hypopharyngeal Cancer; 10 Carcinoma of the Oral Cavity; Introduction; Posttreatment Surveillance; Diagnosis of Recurrence; Principles of Management; Surgical Approaches and Techniques; Outcomes; 11 Carcinoma of the Oropharynx; Epidemiology; Prognostic Factors; Investigations; Principles of Management; Outcomes; 12 Management of Nodal Recurrence; Introduction; Incidence and Distribution of Nodal Recurrence; Evaluation of Nodal Recurrence; Management; Special Considerations; Outcomes.
590			_aWorldCat record variable field(s) change: 650
650		0	_aHead _xCancer _xRadiotherapy.
650		0	_aEvidence-based medicine.
650		0	_aHealth care teams.
650	1	2	_aHead and Neck Neoplasms _xtherapy
650	1	2	_aNeoplasm Recurrence, Local _xtherapy
650	2	2	_aChemoradiotherapy
650	2	2	_aEvidence-Based Medicine
650	2	2	_aPatient Care Team
700	1		_aMehanna, Hisham M., _eeditor.
700	1		_aAng, K. K. _q(K. Kian), _eeditor.
856	4	0	_uhttps://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=534251 _yKingston Hospital NHS Foundation Trust OpenAthens account holders click here for access
938			_aProQuest Ebook Central _bEBLB _nEBL1250443
938			_aebrary _bEBRY _nebr10658207
938			_aEBSCOhost _bEBSC _n534251
938			_aProQuest MyiLibrary Digital eBook Collection _bIDEB _ncis24024960
938			_aThieme _bTHIE _n9783131645715
938			_aYBP Library Services _bYANK _n10197011
942			_n0
994			_a92 _bN$T
999			_c90933 _d90933