000 04623cam a2200517 i 4500
001 ocn854433627
003 OCoLC
005 20221128212333.0
006 m d
007 cr |||||||||||
008 130315s2013 nyua ob 001 0 eng
010 _a 2019713767
040 _aDLC
_beng
_erda
_cDLC
_dYDXCP
_dOCLCF
_dEBLCP
_dAU@
_dSTF
_dN$T
020 _a9781626185852
_qebook
020 _a1626185859
020 _z1626185840
020 _z9781626185845
035 _a608841
_b(N$T)
035 _a(OCoLC)854433627
072 7 _aMED
_x017000
_2bisacsh
049 _aMAIN
245 0 0 _aPsoriasis :
_btypes, triggers, and treatment strategies
_c
_h[E-Book]
264 1 _aNew York :
_bNova Biomedical,
_c[2013]
300 _a1 online resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 0 _aDermatology--laboratory and clinical research
504 _aIncludes bibliographical references and index.
588 _aDescription based on print version record.
505 0 _aPSORIASIS ; Library of Congress Cataloging-in-Publication Data ; Contents ; Preface ; Chapter 1 Keratinocytes in Psoriasis: Key Players in the Disease Process ; Abstract ; I. Skin Homeostasis and Regulation of Function; II. Psoriasis ; 1. Epidemiology ; 2. Clinical Features ; 3. Psoriasis and the Quality of Life; 4. Psoriasis-Associated Co-Morbidities ; 5. Histologic Features ; 6. Psoriasis Phenotypes ; Classification of Psoriasis According to the Clinical Phenotype ; I. Chronic Plaque Psoriasis ; II. Inverse Psoriasis ; III. Guttate Psoriasis ; IV. Erythrodermic Psoriasis.
505 8 _aV. Childhood Psoriasis VI. Pustular Psoriasis ; VII. Nail disease (Psoriatic Onychodystrophy) ; VIII. Psoriatic Arthritis (PsA) ; 7. Therapeutic Armamentarium ; i. Topical Therapy ; ii. Phototherapy ; Ultraviolet B Radiation (UVB) ; Acute ; Chronic ; iii. Systemic Therapy ; Etanercept is Discussed Below as A Representative of this Class of Biologic Therapies; 8. The Mystery of the Disease Origin ; 9. Emerging Drugs; The Controversial Role of DMF; Conclusion; References ; Chapter 2 Types, Triggers and Treatment Strategies of Psoriasis ; Abstract ; Introduction ; Triggering Factors.
505 8 _aInfections Drugs ; Cutaneous Traumas ; Stress and Psychosomatic Factors ; Alcohol ; Smoking ; Clinical Variants ; Psoriasis Vulgaris-Chronic Plaque Psoriasis ; Guttate Psoriasis ; Small Plaque Psoriasis ; Inverse Psoriasis; Seborrhoeic Psoriasis ; Scalp Psoriasis ; Palmoplantar (Non Pustular) Psoriasis ; Nail Psoriasis ; Mucous Membranes ; Pustular Psoriasis ; Erythrodermic Psoriasis ; Treatment; General Considerations ; Topical Treatments ; Corticosteroids; Vitamin D Analogues ; Tazarotene; Salicylic Acid ; Topical Calcineurin Inhibitors ; Anthralin; Coal Tar ; Phototherapy.
505 8 _aUVB Phototherapy Photochemotherapy; Systemic Oral Agents ; Methotrexate; Acitretin ; Cyclosporine ; Other Systemic Drugs; Biologics ; Alefacept ; Efalizumab ; Adalimumab; Etanercept ; Infliximab ; Ustekinumab ; Conclusion ; References ; Chapter 3 A New Strategy for the Treatment of Psoriasis: Keratin 17 (K17) -- Targeting Therapy ; Abstract ; Introduction ; 1. Keratin 17; 1.1. Expression and Location of Keratin 17 ; 1.2. Functions of Keratin 17; 1.3. Keratin 17 as an Immune Regulator ; 2. Keratin 17 and Psoriasis ; 2.1. Expression of K17 in Psoriasis.
505 8 _a2.2. K17 and Psoriasis-Associated Cytokines 2.2.1. Regulation of K17 Expression by IFN- ; 2.2.2. Regulation of K17 Expression by IL-17 and IL-22 ; 2.2.3. Signal-Regulated Kinase Pathway of K17 Expression ; 2.3. Impact of K17 on Psoriatic Autoreactive T Cells ; 2.3.1. Classic Antigens of Psoriatic T Cells in Different Types of Psoriasis; 2.3.2. Sequences in K17 Serving As Psoriatic T Cell-Epitopes ; 2.3. K17 and Autoimmune Positive Feedback Loops in Psoriasis ; 3. K17 and Treatment of Psoriasis ; 3.1. Treatments in Psoriasis ; 3.2. K17 in the Treatments of Psoriasis.
590 _aMaster record variable field(s) change: 050
650 0 _aPsoriasis.
_97575
700 1 _aSmith, Phillip B.
700 1 _aJohnson, Nathan C.
_c(Dermatologist)
856 4 0 _uhttps://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=608841
_yKingston Hospital NHS Foundation Trust OpenAthens account holders click here for access
938 _aYBP Library Services
_bYANK
_n10368082
938 _aEBSCOhost
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_n608841
938 _aProQuest Ebook Central
_bEBLB
_nEBL3022679
942 _n0
994 _a92
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999 _c91316
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