000			05786cam a2200637Ii 4500
001			ocn890310929
003			OCoLC
005			20221128212724.0
006			m d
007			cr cnu---unuuu
008			140910s2014 nju ob 001 0 eng d
040			_aN$T _beng _erda _epn _cN$T _dOCLCF _dCDX _dEBLCP _dOCLCQ _dD6H _dOCLCQ _dOCLCO _dOCLCA _dAGLDB _dOCLCO _dOCLCQ _dOCLCO _dOCLCA _dVNS _dOCLCO _dVTS _dOCLCO _dOCLCA _dSTF _dOCLCO _dM8D _dOCLCO _dOCLCQ _dOCLCA _dOCLCQ _dOCLCA _dOCLCO
019			_a890530150
020			_a9781848163898 _q(electronic bk.)
020			_a1848163894 _q(electronic bk.)
020			_z9781848163881
020			_z1848163886
035			_a839688 _b(N$T)
035			_a(OCoLC)890310929 _z(OCoLC)890530150
060		4	_aWX 218
072		7	_aHEA _x039000 _2bisacsh
072		7	_aMED _x014000 _2bisacsh
072		7	_aMED _x022000 _2bisacsh
072		7	_aMED _x112000 _2bisacsh
072		7	_aMED _x045000 _2bisacsh
049			_aMAIN
245	0	0	_aClinical intensive care medicine _c _h[E-Book]
264		1	_aNew Jersey : _bImperial College Press, _c2014.
300			_a1 online resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	1		_aIntroductory series in medicine ; _vvolume 1
504			_aIncludes bibliographical references and index.
588	0		_aPrint version record.
505	0		_aForeword from the Series Editor; Foreword; Preface; List of Authors; 1 History of Intensive Care; References; 2 Cardiovascular Physiology; 2.1 Introduction; 2.2 The Cardiac Cycle; 2.3 Ventricular Performance and the Determinants of Cardiac Output; 2.3.1 Ventricular preload; 2.3.2 Ventricular afterload; 2.3.3 Venticular contractility and stroke work; 2.3.4 Stroke volume; 2.3.5 Heart rate; 2.3.6 Ventricular interdependence; 2.4 Coronary Blood Flow; 2.5 Peripheral Circulation; 2.6 The Microcirculation; 2.7 Clinical Case; 2.7.1 What is the diagnosis?; 2.7.2 What next?
505	8		_a2.7.3 Lessons to learnReferences; 3 Respiratory Physiology; 3.1 Introduction; 3.2 Regulation of Respiration; 3.3 Mechanics of Ventilation; 3.4 Work of Breathing; 3.5 Ventilation-Perfusion; 3.6 Carbon Dioxide and Interpretation of Expired Alveolar Gas; 3.7 Blood Gases; 3.8 Physiological Effects of Positive-Pressure Ventilation; 3.8.1 Effects on the lungs; 3.8.2 Effects on surfactant; 3.8.3 Effect on the cardiovascular system; 3.8.4 Effect on lymphatics; 3.8.5 Effects on fluid balance; References; 4 Cellular Physiology in Critical Care; 4.1 Oxygen Delivery and Cellular Utilisation.
505	8		_a4.1.1 Mitochondria4.1.1.1 Energy transduction; 4.1.1.2 The mitochondrial respiratory chain; 4.1.2 Control of cellular respiration; 4.1.2.1 Nitric oxide; 4.1.3 Sepsis and mitochondria activity; 4.1.4 Mitochondrial inhibitors; 4.1.4.1 Carbon monoxide; 4.1.4.2 Alcohols; 4.1.4.3 Cyanide; 4.1.4.4 Propofol; 4.1.4.5 Metformin; 4.1.4.6 Statins; 4.1.4.7 Nucleos(t)ide; 4.2 Cell Death in Critical Care; 4.2.1 Apoptosis; 4.2.2 Necrosis; 4.3 Conclusion; 4.4 Clinical Scenario; 4.4.1 History; 4.4.2 Investigations; 4.4.3 Progress; 4.4.4 Further progress; 4.4.5 Answers; References; 5 Cardiovascular Monitoring.
505	8		_a5.1 Purpose of Monitoring5.2 Clinical Examination and Non-Invasive Monitoring; 5.3 Pulse Oximetry; 5.4 Venous Saturations; 5.5 Pulmonary Artery Flotation Catheter; 5.6 Pulse Contour Analysis; 5.7 Oesophageal Doppler; 5.8 Echocardiography; 5.9 Current Approach to Monitoring the Critically Ill Patient; 5.10 Clinical Case; 5.10.1 Comment; References; 6 Vasoactive Agents; 6.1 Definitions; 6.2 The Pressure versus Flow Dilemma; 6.3 Tissue Oxygen Consumption and Supply; 6.3.1 Oxygen supply; 6.3.2 Oxygen consumption; 6.4 Vasodilators: Rationale and Current Treatments; 6.4.1 Nitrates.
505	8		_a6.4.1.1 Glyceryl trinitrate6.4.1.2 Nitroprusside; 6.4.2 Nesiritide; 6.4.3 Nifedipine; 6.4.4 Nicardipine; 6.4.5 Esmolol; 6.4.6 Labetolol; 6.4.7 Hydralazine; 6.4.8 Phentolamine; 6.5 Vasoconstrictors: Rationale and Current Agents; 6.5.1 Noradrenaline; 6.5.2 Dopamine; 6.5.3 Adrenaline; 6.5.4 Vasopressin; 6.5.5 Phenylephrine; 6.5.6 Ephedrine; 6.5.7 Metaraminol; 6.6 Cardiac Output: Advantages and Disadvantages of Pharmacological Augmentation; 6.6.1 Adrenaline; 6.6.2 Dobutamine; 6.6.3 Dopexamine; 6.6.4 Dopamine; 6.6.5 Phosphodiesterase inhibitors; 6.6.6 Levosimendan; 6.6.7 Isoprenaline.
520			_aIntensive care patients are the most critically ill in any hospital and they are a patient group that utilises a disproportionate amount of medical resources. Intensive care medicine, around for about 40 years, is a relatively recent but globally expanding specialty due to a growing geriartric population of discerning demand for health system. The older generation of intensivists are approaching retirement. The middle generation is trained in various medical specialties and then subspecialised in intensive care. These doctors now lead the way in clinical practice, research, management and trai.
590			_aWorldCat record variable field(s) change: 650
650		0	_aCritical care medicine.
650		0	_aClinical medicine.
650	1	2	_aCritical Care
650	2	2	_aClinical Medicine
650	2	2	_aCritical Illness _xtherapy
700	1		_aG�omez, Carlos M. H., _eeditor.
830		0	_aIntroductory series in medicine ; _vv. 1.
856	4	0	_uhttps://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=839688 _yKingston Hospital NHS Foundation Trust OpenAthens account holders click here for access
938			_aCoutts Information Services _bCOUT _n29748687
938			_aProQuest Ebook Central _bEBLB _nEBL1779672
938			_aEBSCOhost _bEBSC _n839688
942			_n0
994			_a92 _bN$T
999			_c91926 _d91926