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024 7 _a10.1515/9783110406344
_2doi
035 _a1106988
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035 _a(OCoLC)945756581
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060 4 _aW 18
072 7 _aHEA
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072 7 _aHEA
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072 7 _aMED
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049 _aMAIN
245 0 0 _aSimulations in medicine :
_bpre-clinical and clinical applications
_c
_h[E-Book]
264 1 _aBerlin ;
_aBoston :
_bDe Gruyter,
_c[2015]
300 _a1 online resource
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _adata file
_2rda
504 _aIncludes bibliographical references and index.
588 0 _aPrint version record.
505 0 _aPreface ; List of authors ; Part I: Molecular level ; 1. Selected aspects of biological network analysis ; 1.1 Introduction ; 1.2 Selected biological databases ; 1.2.1 Case study: Gene Expression Omnibus ; 1.2.2 RegulonDB ; 1.3 Types of biological networks.
505 8 _a1.3.1 Relations between molecules and types of networks 1.3.2 Biochemical pathways ; 1.4 Network development models ; 1.4.1 Selected tools for assembling networks on the basis of gene expression data ; 1.4.2 Selected tools for reconstruction of networks via literature mining.
505 8 _a1.5 Network analysis 1.5.1 Selected tools ; 1.5.2 Cytoscape analysis examples ; 1.6 Summary ; Part II: Cellular level ; 2. Negative feedback inhibition -- Fundamental biological regulation in cells and organisms ; 2.1 Negative feedback-based systems simulations ; 2.1.1 Introduction.
505 8 _a2.1.2 Glossary of Terms 2.1.3 Software model ; 2.1.4 Application manual ; 2.1.5 OS model example ; 2.1.6 Simulation algorithm ; 3. Information -- A tool to interpret the biological phenomena ; Part III: Organ level ; 4. The virtual heart.
505 8 _a5. Modeling figure/ground separation with spiking neurons 5.1 Introduction ; 5.2 Figure/ground separation ; 5.3 Spiking neural networks ; 5.4 Lateral connections via gap junctions ; 5.5 Simulation of a sheet of laterally connected neurons ; 5.6 Basis of our model ; 5.7 Conclusion.
546 _aEnglish.
520 _aThis book describes biological and medical phenomena and how they can be virtually simulated by breaking them down into basic principles. It introduces a wide spectrum of applications, from molecules, tissues, and organs up to the whole body, with a focus on how to use and interpret these simulations. The book is complemented by topics such as serious games and distance medicine.
590 _aWorldCat record variable field(s) change: 650
650 0 _aMedicine
_xSimulation methods.
650 0 _aMedicine
_xComputer simulation.
650 0 _aDigital computer simulation.
650 0 _aComputer simulation.
650 2 _aComputer Simulation
700 1 _aRoterman-Konieczna, Irena,
_eauthor.
856 4 0 _uhttps://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=1106988
_yKingston Hospital NHS Foundation Trust OpenAthens account holders click here for access
938 _aAskews and Holts Library Services
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938 _aAskews and Holts Library Services
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938 _aDe Gruyter
_bDEGR
_n9783110406344
938 _aEBL - Ebook Library
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938 _aEBSCOhost
_bEBSC
_n1106988
938 _aProQuest MyiLibrary Digital eBook Collection
_bIDEB
_ncis31106130
938 _aYBP Library Services
_bYANK
_n12012400
938 _aYBP Library Services
_bYANK
_n12012405
942 _n0
994 _a92
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