Parkinson's disease : diagnosis and clinical management

Parkinson's disease : diagnosis and clinical management [E-Book] - 2nd ed. - New York : Demos, 2008. - 1 online resource (xxviii, 819 pages, 8 unnumbered pages of plates) : illustrations (some color)

Includes bibliographical references and index.

History -- James Parkinson : The Man and the Essay / Paralysis Agitans in the Nineteenth Century / Charcot and Parkinson's Disease / Timeline of Parkinson's Disease History Since 1900 / Clinical Presentation -- Epidemiology / Cardinal Features of Early Parkinson's Disease / Gait Disturbances / Sensory Symptoms / Voice, Speech, and Swallowing Disorders / Gastrointestinal Features / Autonomic Dysfunction / Sleep Disorders / Natural History / Clinical Rating Scales / Behavioral and Psychiatric Manifestations -- Dementia / Depression / Anxiety and Panic / Apathy and Amotivation / Impulse-control Disorders / Pathology and Neurochemistry -- Neuropathology / Neurochemistry / Basal Ganglia : Anatomy and Physiology / Dopamine Receptor Diversity / Biomarkers -- Status of Biological Markers / Positron Emission Tomography / Single Photon Emission Computed Tomography / Magnetic Resonance Imaging / Controversies in Neuroimaging / Pathogenesis and Etiology -- Animal Models / Pathogenesis : Oxidative Stress, Mitochondrial Dysfunction, and Excitotoxicity / The Concept and Mechanisms of Programmed Cell Death / Protein Aggregation / Etiology : The Role of Environment and Genetics / The Impact of MPTP on Parkinson's Disease Research : Past, Present, and Future / Rotenone and Other Toxins / Inflammation / Genetics / Drugs -- Levodopa : A Pharmacologic Miracle Four Decades Later / Amantadine and Anticholinergics / Monoamine Oxidase Inhibitors / Dopamine Agonists / Catechol-O-Methyltransferase Inhibitors / Excitatory Amino Acid Antagonists / Adenosine AA Receptor Antagonists / Complementary and Alternative Medicine / Treatment Issues -- Motor Fluctuations and Dyskinesia / Fluctuations of Nonmotor Symptoms / Psychosis and Other Behaviors / Treatment of Dementia / Status of Neuroprotective Therapies / Symptomatic Treatment Approaches for Early Parkinson's Disease / Progress in Gene Therapy / Genetic Testing / Surgery -- Deep Brain Stimulation / Neural Transplantation : Yesterday, Today, and Tomorrow / Stereotactic Pallidotomy and Thalamotomy / Subtypes of Parkinsonism -- Parkinson's-plus Disorders / Symptomatic Parkinsonism / Other Issues -- Outcome Measures / Family Caregiving / Economics / Driving / The Patient's Perspective / Anthony E. Lang -- Stewart A. Factor and William J. Weiner -- Elan D. Louis -- Christopher G. Goetz -- William J. Weiner and Stewart A. Factor -- Michele L. Rajput, Ali H. Rajput, and Alexander Rajput -- Ali Samii -- Nir Giladi and Alice Nieuwboer -- Richard M. Zweig and Debra Elliott -- Shimon Sapir, Lorraine O. Ramig, and Cynthia M. Fox -- Eamonn M.M. Quigley -- Thomas C. Chelimsky -- Cynthia Louise Comella -- Michael Pourfar, Andrew Feigin, and David Eidelberg -- Stephen T. Gancher -- Karen S. Marder and Diane M. Jacobs -- William M. McDonald -- Irene Hegeman Richard and Roger Kurlan -- Lisa M. Shulman and Mackenzie Carpenter -- Valerie Voon and Susan H. Fox -- Dennis W. Dickson -- Jose Martin Rabey and Richard Stanley Burns -- Thomas Wichmann, Yoland Smith, and Jerrold L. Vitek -- Deborah C. Mash -- E. Ray Dorsey, Robert G. Holloway, and Bernard M. Ravina -- Joel S. Perlmutter -- Andrew B. Newberg and Paul D. Acton -- Tao Wu and Mark Hallett -- Paul Morrish -- Paul S. Fishman -- Claire Henchcliffe and M. Flint Beal -- Robert E. Burke -- Leonard Petrucelli, Ana Maria Cuervo, and Serge Przedborski -- Caroline M. Tanner -- J. William Langston -- Ranjita Betarbet and J. Timothy Greenamyre -- Ronald F. Pfeiffer -- Denise M. Kay, Jennifer S. Montimurro, and Haydeh Payami -- Tanya Simuni and Howard Hurtig -- Charles H. Adler -- Alexander Rajput, Theresa A. Zesiewicz, and Robert A. Hauser -- Puiu F. Nisipeanu and Amos D. Korczyn -- Cheryl Waters -- James G. Greene -- Rukmini Menon and Mark A. Stacy -- Jorge L. Juncos -- Steven A. Gunzler and John G. Nutt -- Jacob I. Sage -- Eric S. Molho -- Karen E. Anderson -- Andrew D. Siderowf and Matthew B. Stern -- J. Eric Ahlskog -- Hideki Mochizuki and M. Maral Mouradian -- John Hardy and Aideen McInermey-Leo -- Norika Malhado-Chang, Ron L. Alterman, and Michele Tagliati -- Paul Greene -- Robert E. Gross and Andres M. Lozano -- Meredith Broderick and David E. Riley -- Sanjay S. Iyer, William T. Garrett, and Kapil D. Sethi -- Lisa M. Shulman -- Julie H. Carter, Barbara J. Stewart, and Patricia G. Archbold -- E. Ray Dorsey, Andrew D. Siderowf, and Robert G. Holloway -- Stewart A. Factor and William J. Weiner -- David S. Heydrick. Foreword / Part I. Part II. Part III. Part IV. Part V. Part VI. Part VII. Part VIII. Part IX. Part X. Part XI.

Parkinson's disease (PD) is the second most common neurodegenerative disease in the world. Still the only major text on the subject, the completely revised and updated second edition of Parkinson's Disease: Diagnosis and Clinical Management comes at a time when specialists have made important advances in our understanding of the etiology, pathogenesis, investigation, and management of Parkinson's disease.


English.

9781934559871 1934559873 1281975192 9781281975195 9786611975197 6611975195

DNLM


Parkinson's disease.
Symptomatic Parkinson's disease.
Parkinson Disease--diagnosis
Parkinson Disease--therapy
Parkinson Disease, Secondary
Parkinson Disease
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