Parkinson's disease : diagnosis and clinical management [E-Book]

Includes bibliographical references and index.

Foreword / Anthony E. Lang -- Part I. History -- James Parkinson : The Man and the Essay / Stewart A. Factor and William J. Weiner -- Paralysis Agitans in the Nineteenth Century / Elan D. Louis -- Charcot and Parkinson's Disease / Christopher G. Goetz -- Timeline of Parkinson's Disease History Since 1900 / William J. Weiner and Stewart A. Factor -- Part II. Clinical Presentation -- Epidemiology / Michele L. Rajput, Ali H. Rajput, and Alexander Rajput -- Cardinal Features of Early Parkinson's Disease / Ali Samii -- Gait Disturbances / Nir Giladi and Alice Nieuwboer -- Sensory Symptoms / Richard M. Zweig and Debra Elliott -- Voice, Speech, and Swallowing Disorders / Shimon Sapir, Lorraine O. Ramig, and Cynthia M. Fox -- Gastrointestinal Features / Eamonn M.M. Quigley -- Autonomic Dysfunction / Thomas C. Chelimsky -- Sleep Disorders / Cynthia Louise Comella -- Natural History / Michael Pourfar, Andrew Feigin, and David Eidelberg -- Clinical Rating Scales / Stephen T. Gancher -- Part III. Behavioral and Psychiatric Manifestations -- Dementia / Karen S. Marder and Diane M. Jacobs -- Depression / William M. McDonald -- Anxiety and Panic / Irene Hegeman Richard and Roger Kurlan -- Apathy and Amotivation / Lisa M. Shulman and Mackenzie Carpenter -- Impulse-control Disorders / Valerie Voon and Susan H. Fox -- Part IV. Pathology and Neurochemistry -- Neuropathology / Dennis W. Dickson -- Neurochemistry / Jose Martin Rabey and Richard Stanley Burns -- Basal Ganglia : Anatomy and Physiology / Thomas Wichmann, Yoland Smith, and Jerrold L. Vitek -- Dopamine Receptor Diversity / Deborah C. Mash -- Part V. Biomarkers -- Status of Biological Markers / E. Ray Dorsey, Robert G. Holloway, and Bernard M. Ravina -- Positron Emission Tomography / Joel S. Perlmutter -- Single Photon Emission Computed Tomography / Andrew B. Newberg and Paul D. Acton -- Magnetic Resonance Imaging / Tao Wu and Mark Hallett -- Controversies in Neuroimaging / Paul Morrish -- Part VI. Pathogenesis and Etiology -- Animal Models / Paul S. Fishman -- Pathogenesis : Oxidative Stress, Mitochondrial Dysfunction, and Excitotoxicity / Claire Henchcliffe and M. Flint Beal -- The Concept and Mechanisms of Programmed Cell Death / Robert E. Burke -- Protein Aggregation / Leonard Petrucelli, Ana Maria Cuervo, and Serge Przedborski -- Etiology : The Role of Environment and Genetics / Caroline M. Tanner -- The Impact of MPTP on Parkinson's Disease Research : Past, Present, and Future / J. William Langston -- Rotenone and Other Toxins / Ranjita Betarbet and J. Timothy Greenamyre -- Inflammation / Ronald F. Pfeiffer -- Genetics / Denise M. Kay, Jennifer S. Montimurro, and Haydeh Payami -- Part VII. Drugs -- Levodopa : A Pharmacologic Miracle Four Decades Later / Tanya Simuni and Howard Hurtig -- Amantadine and Anticholinergics / Charles H. Adler -- Monoamine Oxidase Inhibitors / Alexander Rajput, Theresa A. Zesiewicz, and Robert A. Hauser -- Dopamine Agonists / Puiu F. Nisipeanu and Amos D. Korczyn -- Catechol-O-Methyltransferase Inhibitors / Cheryl Waters -- Excitatory Amino Acid Antagonists / James G. Greene -- Adenosine AA Receptor Antagonists / Rukmini Menon and Mark A. Stacy -- Complementary and Alternative Medicine / Jorge L. Juncos -- Part VIII. Treatment Issues -- Motor Fluctuations and Dyskinesia / Steven A. Gunzler and John G. Nutt -- Fluctuations of Nonmotor Symptoms / Jacob I. Sage -- Psychosis and Other Behaviors / Eric S. Molho -- Treatment of Dementia / Karen E. Anderson -- Status of Neuroprotective Therapies / Andrew D. Siderowf and Matthew B. Stern -- Symptomatic Treatment Approaches for Early Parkinson's Disease / J. Eric Ahlskog -- Progress in Gene Therapy / Hideki Mochizuki and M. Maral Mouradian -- Genetic Testing / John Hardy and Aideen McInermey-Leo -- Part IX. Surgery -- Deep Brain Stimulation / Norika Malhado-Chang, Ron L. Alterman, and Michele Tagliati -- Neural Transplantation : Yesterday, Today, and Tomorrow / Paul Greene -- Stereotactic Pallidotomy and Thalamotomy / Robert E. Gross and Andres M. Lozano -- Part X. Subtypes of Parkinsonism -- Parkinson's-plus Disorders / Meredith Broderick and David E. Riley -- Symptomatic Parkinsonism / Sanjay S. Iyer, William T. Garrett, and Kapil D. Sethi -- Part XI. Other Issues -- Outcome Measures / Lisa M. Shulman -- Family Caregiving / Julie H. Carter, Barbara J. Stewart, and Patricia G. Archbold -- Economics / E. Ray Dorsey, Andrew D. Siderowf, and Robert G. Holloway -- Driving / Stewart A. Factor and William J. Weiner -- The Patient's Perspective / David S. Heydrick.

Print version record.

Parkinson's disease (PD) is the second most common neurodegenerative disease in the world. Still the only major text on the subject, the completely revised and updated second edition of Parkinson's Disease: Diagnosis and Clinical Management comes at a time when specialists have made important advances in our understanding of the etiology, pathogenesis, investigation, and management of Parkinson's disease.

English.

WorldCat record variable field(s) change: 650