Neurological disorders : (Record no. 90993)

MARC details
000 -LEADER
fixed length control field 04984cam a2200577 i 4500
001 - CONTROL NUMBER
control field ocn829236612
003 - CONTROL NUMBER IDENTIFIER
control field OCoLC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20221128212141.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION
fixed length control field m d
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr |||||||||||
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 120503t20122012nyua ob 001 0 eng
010 ## - LIBRARY OF CONGRESS CONTROL NUMBER
LC control number 2020686181
040 ## - CATALOGING SOURCE
Original cataloging agency DLC
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9781622570560
Qualifying information ebook
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 1622570561
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Cancelled/invalid ISBN 9781622570423
Qualifying information hardcover
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Cancelled/invalid ISBN 1622570421
035 ## - SYSTEM CONTROL NUMBER
System control number 535131
-- (N$T)
035 ## - SYSTEM CONTROL NUMBER
System control number (OCoLC)829236612
042 ## - AUTHENTICATION CODE
Authentication code pcc
072 #7 - SUBJECT CATEGORY CODE
Subject category code HEA
Subject category code subdivision 039110
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED
Subject category code subdivision 056000
Source bisacsh
049 ## - LOCAL HOLDINGS (OCLC)
Holding library MAIN
245 00 - TITLE STATEMENT
Title Neurological disorders :
Subtitle new research
Statement of responsibility, etc
Medium [E-Book]
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture New York :
Name of producer, publisher, distributor, manufacturer Nova Biomedical, Science Science Publishers, Incorporated,
Date of production, publication, distribution, manufacture, or copyright notice [2012]
300 ## - PHYSICAL DESCRIPTION
Physical description 1 online resource.
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
490 0# - SERIES TITLE
Series statement Neuroscience research process
490 0# - SERIES TITLE
Series statement Neurology--laboratory and clinical research developments
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes bibliographical references and index.
505 0# - CONTENTS
Contents NEUROLOGICAL DISORDERS ; NEUROLOGICAL DISORDERS ; Contents; Preface; Advanced Structural and Functional MRI Techniques in Parkinson's Disease; Abstract; Introduction; MR Morphometry; Diffusion MR Imaging; Functional MRI; Motor fMRI; Cognitive fMRI; Resting-State fMRI; Conclusion; References; Neuropoietic Cytokines and Neural Injury: Alterations in JAK2/STAT3 Signaling Associated with Aging; Abstract; 1. Introduction; 1.1. Neuropoietic Cytokine Family; 1.2. Role of the gp130 Cytokine Receptor Complex; 1.3. Role of Janus Kinases (Jaks)
505 8# - CONTENTS
Contents 1.4. Activation of Signal Transducer and Activator of Transcription 3 (STAT3)1.5. Effects of Phospho-STAT3 (pSTAT3); Cell Survival; Remodeling the Cellular Environment; Regulating Oxidative Stress; Immune Tolerance; Role of the Phosphorylation Site; 1.6. Regulating pSTAT3: Role of Negative Regulators; Suppressors of Cytokine Signaling (SOCS); Protein Inhibitors of Activated Stats (PIAS); Protein Tyrosine Phosphatases (PTP); 2. Discussion; 2.1. Changes in Neural Injury; Stroke; Traumatic Brain Injury; 2.2. JAK2/STAT3 Regulation Altered with Aging; 2.3. Significance of Phosphorylation Site.
505 8# - CONTENTS
Contents 3. Future Directions3.1. Elucidate the Role of STAT3 across Cell Types; 3.2. Modulating Beneficial vs. Detrimental Effects; 3.3. Identifying Injury-Associated Changes; 3.4. Understanding and Manipulating Regulatory Processes for Therapeutic Benefit; 3.5. The IL-6 and IL-10 Signaling Dynamic; 3.6. Therapeutic Development: Challenges of Inhibition; Conclusion; Acknowledgments; References; Neurological Complications Associated with Anti-Tumor Necrosis Factor Alpha (TNF-<U+0041>) Treatment; Abstract; Introduction; Tumor Necrosis Factor (TNF)-<U+0041>; Pathogenicity of TNF-<U+0041> in Neurological Disorder.
505 8# - CONTENTS
Contents Anti-TNF-<U+0041> or TNF-<U+0041> Antagonist DrugAnti-TNF-<U+0041> and Neurological Disorders; Conclusion; References; Effect of Aging on Changes of Nociception and Cav2 1 Expression Patterns in Seven Inbred Mouse Strains; Abstract; Introduction; Materials and Methods; Animals; Nociceptive Assays; Statistical Analysis of Behavioral Tests; Real-Time qRT-PCR Analysis; Results; Pain-Related Behavioral Tests; Expression Tests of Cav2 Family Members with Real-Time qRT-PCR Assay; Discussion; Conclusion; Acknowledgments; References; Polymeric Intracorporeal Devices for the Management of Neurological Disorders.
505 8# - CONTENTS
Contents Abstract1. Introduction; 2. Polymer-Based Implantable Devices for Major CNS Disorders; 2.1. Intracranial Implants; 2.1.1. Drug Delivery Approaches Employed to Traverse the Blood Brain Barrier; 2.1.1.1. Ethylene Vinyl Acetate Copolymers Avac as a Prototype; Biocompatible Polymer Employed for Local Drug Delivery to the Brain; 2.1.1.2. Silk-Based Polymers as an Alternative to Synthetic Drug Delivery-Systems for the Treatment of Epilepsy; 2.1.2. Application of Polymer-Based Implantable Devices in Parkinson's Disease; 2.1.2.1. Biocompatible Dopamine-Loaded Polymeric Matrix Device.
590 ## - LOCAL NOTE (RLIN)
Local note Master record variable field(s) change: 050, 082
650 #0 - SUBJECT HEADINGS
Subject term Nervous system
General subdivision Diseases.
650 #0 - SUBJECT HEADINGS
Subject term Neurology.
700 1# - ADDED PERSONAL NAME
Added personal author Thomas, Chloe E.,
Relator term editor of compilation.
700 1# - ADDED PERSONAL NAME
Added personal author Moore, Jayden R.,
Relator term editor of compilation.
856 40 - ONLINE RESOURCE
Uniform Resource Identifier <a href="https://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=535131">https://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=535131</a>
Link text Kingston Hospital NHS Foundation Trust OpenAthens account holders click here for access
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Suppress in OPAC Do not Suppress in OPAC
588 ## - SOURCE OF DESCRIPTION NOTE
Source of description note Description based on print version record and cip data provided by publisher.
938 ## -
-- YBP Library Services
-- YANK
-- 10251442
938 ## -
-- EBSCOhost
-- EBSC
-- 535131
938 ## -
-- ebrary
-- EBRY
-- ebr10683149
938 ## -
-- ProQuest Ebook Central
-- EBLB
-- EBL3021491
994 ## -
-- 92
-- N$T
Holdings
Withdrawn status Lost status Damaged status Not for loan Home library Current library Shelving location Date acquired Source of acquisition Total Checkouts Date last seen Uniform Resource Identifier Price effective from Koha item type
        Stenhouse Library Stenhouse Library   28/11/2022 eBook EBSCO clinical collection   28/11/2022 https://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=535131 28/11/2022 Electronic book
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