MARC details
000 -LEADER |
fixed length control field |
04984cam a2200577 i 4500 |
001 - CONTROL NUMBER |
control field |
ocn829236612 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
OCoLC |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20221128212141.0 |
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION |
fixed length control field |
m d |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr ||||||||||| |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
120503t20122012nyua ob 001 0 eng |
010 ## - LIBRARY OF CONGRESS CONTROL NUMBER |
LC control number |
2020686181 |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
DLC |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
ISBN |
9781622570560 |
Qualifying information |
ebook |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
ISBN |
1622570561 |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
Cancelled/invalid ISBN |
9781622570423 |
Qualifying information |
hardcover |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
Cancelled/invalid ISBN |
1622570421 |
035 ## - SYSTEM CONTROL NUMBER |
System control number |
535131 |
-- |
(N$T) |
035 ## - SYSTEM CONTROL NUMBER |
System control number |
(OCoLC)829236612 |
042 ## - AUTHENTICATION CODE |
Authentication code |
pcc |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
HEA |
Subject category code subdivision |
039110 |
Source |
bisacsh |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
MED |
Subject category code subdivision |
056000 |
Source |
bisacsh |
049 ## - LOCAL HOLDINGS (OCLC) |
Holding library |
MAIN |
245 00 - TITLE STATEMENT |
Title |
Neurological disorders : |
Subtitle |
new research |
Statement of responsibility, etc |
|
Medium |
[E-Book] |
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
Place of production, publication, distribution, manufacture |
New York : |
Name of producer, publisher, distributor, manufacturer |
Nova Biomedical, Science Science Publishers, Incorporated, |
Date of production, publication, distribution, manufacture, or copyright notice |
[2012] |
300 ## - PHYSICAL DESCRIPTION |
Physical description |
1 online resource. |
336 ## - CONTENT TYPE |
Content type term |
text |
Content type code |
txt |
Source |
rdacontent |
337 ## - MEDIA TYPE |
Media type term |
computer |
Media type code |
c |
Source |
rdamedia |
338 ## - CARRIER TYPE |
Carrier type term |
online resource |
Carrier type code |
cr |
Source |
rdacarrier |
490 0# - SERIES TITLE |
Series statement |
Neuroscience research process |
490 0# - SERIES TITLE |
Series statement |
Neurology--laboratory and clinical research developments |
504 ## - BIBLIOGRAPHY, ETC. NOTE |
Bibliography, etc |
Includes bibliographical references and index. |
505 0# - CONTENTS |
Contents |
NEUROLOGICAL DISORDERS ; NEUROLOGICAL DISORDERS ; Contents; Preface; Advanced Structural and Functional MRI Techniques in Parkinson's Disease; Abstract; Introduction; MR Morphometry; Diffusion MR Imaging; Functional MRI; Motor fMRI; Cognitive fMRI; Resting-State fMRI; Conclusion; References; Neuropoietic Cytokines and Neural Injury: Alterations in JAK2/STAT3 Signaling Associated with Aging; Abstract; 1. Introduction; 1.1. Neuropoietic Cytokine Family; 1.2. Role of the gp130 Cytokine Receptor Complex; 1.3. Role of Janus Kinases (Jaks) |
505 8# - CONTENTS |
Contents |
1.4. Activation of Signal Transducer and Activator of Transcription 3 (STAT3)1.5. Effects of Phospho-STAT3 (pSTAT3); Cell Survival; Remodeling the Cellular Environment; Regulating Oxidative Stress; Immune Tolerance; Role of the Phosphorylation Site; 1.6. Regulating pSTAT3: Role of Negative Regulators; Suppressors of Cytokine Signaling (SOCS); Protein Inhibitors of Activated Stats (PIAS); Protein Tyrosine Phosphatases (PTP); 2. Discussion; 2.1. Changes in Neural Injury; Stroke; Traumatic Brain Injury; 2.2. JAK2/STAT3 Regulation Altered with Aging; 2.3. Significance of Phosphorylation Site. |
505 8# - CONTENTS |
Contents |
3. Future Directions3.1. Elucidate the Role of STAT3 across Cell Types; 3.2. Modulating Beneficial vs. Detrimental Effects; 3.3. Identifying Injury-Associated Changes; 3.4. Understanding and Manipulating Regulatory Processes for Therapeutic Benefit; 3.5. The IL-6 and IL-10 Signaling Dynamic; 3.6. Therapeutic Development: Challenges of Inhibition; Conclusion; Acknowledgments; References; Neurological Complications Associated with Anti-Tumor Necrosis Factor Alpha (TNF-<U+0041>) Treatment; Abstract; Introduction; Tumor Necrosis Factor (TNF)-<U+0041>; Pathogenicity of TNF-<U+0041> in Neurological Disorder. |
505 8# - CONTENTS |
Contents |
Anti-TNF-<U+0041> or TNF-<U+0041> Antagonist DrugAnti-TNF-<U+0041> and Neurological Disorders; Conclusion; References; Effect of Aging on Changes of Nociception and Cav2 1 Expression Patterns in Seven Inbred Mouse Strains; Abstract; Introduction; Materials and Methods; Animals; Nociceptive Assays; Statistical Analysis of Behavioral Tests; Real-Time qRT-PCR Analysis; Results; Pain-Related Behavioral Tests; Expression Tests of Cav2 Family Members with Real-Time qRT-PCR Assay; Discussion; Conclusion; Acknowledgments; References; Polymeric Intracorporeal Devices for the Management of Neurological Disorders. |
505 8# - CONTENTS |
Contents |
Abstract1. Introduction; 2. Polymer-Based Implantable Devices for Major CNS Disorders; 2.1. Intracranial Implants; 2.1.1. Drug Delivery Approaches Employed to Traverse the Blood Brain Barrier; 2.1.1.1. Ethylene Vinyl Acetate Copolymers Avac as a Prototype; Biocompatible Polymer Employed for Local Drug Delivery to the Brain; 2.1.1.2. Silk-Based Polymers as an Alternative to Synthetic Drug Delivery-Systems for the Treatment of Epilepsy; 2.1.2. Application of Polymer-Based Implantable Devices in Parkinson's Disease; 2.1.2.1. Biocompatible Dopamine-Loaded Polymeric Matrix Device. |
590 ## - LOCAL NOTE (RLIN) |
Local note |
Master record variable field(s) change: 050, 082 |
650 #0 - SUBJECT HEADINGS |
Subject term |
Nervous system |
General subdivision |
Diseases. |
650 #0 - SUBJECT HEADINGS |
Subject term |
Neurology. |
700 1# - ADDED PERSONAL NAME |
Added personal author |
Thomas, Chloe E., |
Relator term |
editor of compilation. |
700 1# - ADDED PERSONAL NAME |
Added personal author |
Moore, Jayden R., |
Relator term |
editor of compilation. |
856 40 - ONLINE RESOURCE |
Uniform Resource Identifier |
<a href="https://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=535131">https://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=535131</a> |
Link text |
Kingston Hospital NHS Foundation Trust OpenAthens account holders click here for access |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Suppress in OPAC |
Do not Suppress in OPAC |
588 ## - SOURCE OF DESCRIPTION NOTE |
Source of description note |
Description based on print version record and cip data provided by publisher. |
938 ## - |
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YBP Library Services |
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YANK |
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10251442 |
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EBSCOhost |
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EBSC |
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535131 |
938 ## - |
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ebrary |
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EBRY |
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ebr10683149 |
938 ## - |
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ProQuest Ebook Central |
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EBLB |
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EBL3021491 |
994 ## - |
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92 |
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N$T |